Xanthohumol, a prenylated flavonoid found in hops and beer, possesses a long-standing reputation to improve health. Xanthohumol’s cytotoxicity to a wide variety of cancer cell lines is well-established. Herein we provide further insight into the cytotoxicity of not only xanthohumol, but also its non-estrogenic derivatives, to a number of colonic...
Differences in the chemical composition of calcified structures can be used to reveal natal origins, connectivity, metapopulation structure, and reconstruct the environmental history or movement patterns of many marine organisms. Sharks, skates, and rays (elasmobranchs) lack the calcified structures, known as otoliths, that are typically used for geochemical studies of...
Freshwater systems cycle carbon along a spatial and temporal biogeochemical continuum, across which ecosystem processes contribute to transformations of organic matter (OM). Various ecological constraints impact rates OM transformation and production and consumption of the energetic end of respiration, methane. Microbiological processing and complete reduction of carbon substrates to methane...
DNA is often described as the “blueprint for life”. In eukaryotes this information is contained within linear chromosomes of varying size and number. During cell division, the chromosomes must be faithfully segregated into each daughter cell to avoid disease and sustain life. This process is carried out by the kinetochore...
In horticultural nurseries for container-grown plants, production and sales have been threatened by the presence of a quarantined plant pathogen, Phytophthora ramorum (causal agent of sudden oak death). Infested nursery beds are an important source of P. ramorum, which can initiate disease through movement with surface water to infect roots...
Coral reef ecosystems continue to be significantly altered by disease epizootics, but why some host populations remain resistant while others succumb to outbreaks remains unknown. Research across diverse animal and plant host systems has revealed that disease severity is strongly influenced by host genetics and by environmental influences on both...
A simulation model capable of execution on a programmable
calculator was developed to study voluntary intake,
liveweight change, and fertility of grade Zebu cows in the
Llanos of Colombia. Organic nitrogen in the diet and meta
bolic weight were used to predict intake; age, liveweight,
and energy concentration were the...
During the first full school year of the Covid-19 pandemic, two central contexts for adolescent development—home and school—changed utterly. In Oregon, most middle- and high schoolers attended school entirely remotely from the beginning of the pandemic, in March, 2020, through the end of April, 2021, removing both the supports available...
On coral reefs, disturbances rarely occur in isolation. Global stressors such as increasing seawater temperature often coincide with local stressors like nutrient pollution. In the face of increasing anthropogenic stress, corals can function as environmental sentinels, although little is known about how multiple stressors interact to disrupt their associated bacterial...
Mathematical modeling plays a pivotal role in understanding the mechanism of radiation-induced cellular effects, and also in quantifying the radiation risk to the cell. However, there are still compelling challenges facing the conventional modeling in radiobiology, such as lacking a generalized theory structure of quantifying target effect and non-target effect...