T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds are well-recognized for their immunosuppressive activity, which is mediated through an intracellular receptor and transcription factor, aryl hydrocarbon receptor (AhR). Laboratory animals exposed to TCDD are less resistant to infection and have severely impaired humoral and cell-mediated immune responses. This dissertation addressed the hypothesis that...
The immune system has been identified as a very sensitive target for the toxic effects of 2,3,7,S-tetrachlorodibenzo-p-dioxin (TCDD). Exposure to TCDD has been shown to disrupt the generation of both cell-mediated and humoral T cell-dependent immunity in laboratory animals; however, the mechanism remains unknown. In this dissertation, the hypothesis is...
In the problem of testing the median using a random sample from a
certain distribution, and if no other parametric family is suggested,
the t-test is known to be the optimal procedure when this distribution
is normal. If the sample appears to be non-normal, one has the choice
either to...
A study of populations characteristics of T. turgidum ssp.
carthlicum and T. aestivum ssp. carthlicoides was completed using
numerical analysis. A sample of 74 accessions of ssp. carthlicum
and 20 of ssp. carthlicoides were scored for 46 characters. It was
established that three morphological distinguishable groups of ssp.
carthlicum can...
The spectrophotometric titration of the tyrosine residues,
their reaction with N-acetylimidazole, and the effect of pH on the
thermally induced conformational transition of ribonuclease T₁ have
been investigated. The results of spectrophotometric titration in
0.20 M KCl/0.001 M sodium phosphate suggest that titration of the
tyrosine residues occurs in two...
The immune toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been studied for over 35 years, but only recently has the profound immune suppression associated with TCDD exposure been linked to induction of regulatory T cells (Tregs). The effects of TCDD are mediated through binding the aryl hydrocarbon receptor (AhR), a ligand-activated transcription...
Proper immune function is indispensable, as failure to mount an immune response against a pathogen can lead to serious complications or even death. T cells act by enhancing the activation of phagocytic cells as well as the activation of B cells. Their widespread influence on an immune response makes optimal...
The purpose of this study was to determine if
students' school-related attitudes are significantly
affected by teacher classroom discipline management based
upon concepts contained in Judicious Discipline: A Constitutional
Perspective for School Rules (Gathercoal, 1986).
The data relative to student school-related attitudes
of elementary, middle, and high school students toward...
The research examines the effect of restricted head and neck movement on
driving performance as measured by decision time at T-intersections. The traffic
safety and human factors literature was reviewed, and very little was found
concerning drivers with physical limitations. T-intersections were selected for
study because most accidents involving drivers...
Parasitic infections and immune challenges can affect host reproductive fitness and, ultimately, the evolution of host populations in a myriad of ways. The fitness implications of parasitic infections range from increased host mortality to subtle changes in reproductive investment. From alterations of behaviors, sexual signaling, and competitive ability to changes...
Small mountainous watersheds are disproportionate sources of land-derived particulate organic matter (POM) to long-term sinks like lake bottoms and the ocean. As such, these ecosystems are an essential component of the global carbon cycle. The burial of POM in lacustrine and marine sediments contributes to the drawdown of atmospheric CO2...
Thermochemical water splitting cycles have been conceptualized and researched for over half a century, yet to this day none are commercially viable. The heavily studied Sulfur-Iodine cycle has been stalled in the early development stage due to a difficult HI-H₂O separation step and material compatibility issues. In an effort to...
With the increasing international focus on transboundary cooperation as a part of the Sustainable Development Goal (SDG) Framework, there is global recognition of transboundary water cooperation as a tool for improved governance and management of transboundary surface and groundwaters. Yet, there is not an agreed upon definition of transboundary water...
In higher vertebrates, normal digestion and absorption by the
gastrointestinal tract are dependent on the orderly and controlled
transit of intraluminal contents. A relationship between fluid
passage through the gut and absorption from the gut has yet to be
examined in fish. In marine teleosts, the osmolality and ion concentration...
A sequence of soil profiles was sampled along a climate-vegetation transect on the dated Mazama pumice fall in central
Oregon. The <2 μ size fraction from each sample was characterized
with respect to the relative significance of amorphous and
crystalline components, and the individual minerals of the latter
group were...
The aryl hydrocarbon receptor (AhR) has recently been described as a novel therapeutic target, given the potent suppression of multiple immune-mediated diseases following activation by the prototypic ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In the parent-into-F1 graft-versus-host (GVH) model, suppression of the cytotoxic T-lymphocyte (CTL) response is associated with the presence of CD25⁺CTLA-4⁺IL-10⁺Foxp3[superscript...
Observations were made on silage pH, chemical composition and 24hr in vitro dry matter digestion (IVDMD) to evaluate effects of various additives ensiled with annual ryegrass straw. Additives were compared in factorial designed trials utilizing .95 1 glass jar silos. Selection of additives used in each subsequent trial was based...
The study was conducted on the San Dimas Experimenta1 Forest in
southern California. It deals with a field and laboratory evaluation
of several physical and hydraulic properties of the weathered parent
material and suggests how these properties may relate to flood runoff
problems.
A simple correlation analysis shows that only...
The relationships of serum T₄
(thyroxine) levels and liver
nicotinamide nucleotide coenzyme (NAD and NADP) levels with production
of traits of beef cattle were investigated at both weaning (182
kg) and following performance testing (363 kg). In addition, the value
of these parameters as selection criteria for improved performance
was...
Analytical techniques are utilized in a wide variety of applications. Traditionally, analytical measurements are achieved by trained personnel in a laboratory setting using expensive scientific instruments, which limits their applicability in resource-limited areas and point-of-care applications. Therefore, the concept of enabling these laboratory-based qualitative and quantitative assays in microfluidic device...
Three areas of liquid state theory are considered.
First, Monte Carlo computer simulation of a two-dimensional hard
disk fluid with an imbedded ellipse was undertaken to determine how a
non-spherical molecule affects intermolecular ordering. The
elliptical molecule (with axial ratios of 2, 5 and 10) altered the
isotropic distribution of...
Setaria lutescens (yellow foxtail) plants, grown from five seed
sources were compared in California. Seed sources were: Connecticut,
Iowa, Massachusetts, Pennsylvania and California. Morphological
and physiological differences between biotypes include: plant
size, growth habit, time required to mature and reproductive capa
city. Most significant is the prostrate habit of the...
Incubation experiments with an acid poorly drained soil have
shown that the application of neutral soluble salts influenced the level
of extractable Mn. The application of a salt which lowered the soil
pH either increased the extractable Mn or retarded the oxidation
and/or fixation of extractable Mn. This effect was...
Nonthermal electrical plasmas can allow energy intensive reactions to occur without the use of high operating temperatures or pressures. This is because the collisions of electrons accelerated through an electric field with molecules is the cause of reactions as opposed to thermal collisions between molecules. In this study, the production...
The height of an algebraic number A is a measure of how arithmetically complicated A is. We say A is totally p-adic if the minimal polynomial of A splits completely over the field of p-adic numbers. In this paper, we investigate what can be said about the smallest nonzero height...
L-pipecolic acid (L-PA) is the higher homolog of proline. It occurs naturally in
many organisms, including primates, as an intermediate in lysine degradation. The
pathway by which lysine is converted into L-pipecolic acid employs the enzyme Lpipecolate
oxidase (L-PO), and appears to be tissue specific to the central nervous system...
The Comprehensive Nuclear-Test-Ban Treaty (CTBT) prohibits the testing of nuclear weapons on the face of the earth. The detection of atmospheric radioxenon (131mXe, 133m/133Xe, and 135Xe) plays an important role in the identification of sub-surface clandestine nuclear weapon explosions. Since the radioxenon identified above decay via two radiation in coincidence,...
Alcohol is a widely consumed, nonessential, bioactive nutrient with end-organ effects on the skeleton. Moderate levels of alcohol consumption are generally associated with increased bone mineral density (BMD), whereas higher intake levels result in reduced bone formation, bone loss, and increased risk for osteoporotic fracture. Given the negative impact of...
Detailed phytosociological and physical data were gathered from six grass-fern balds in the Oregon Coast Range, Monmouth Peak, Grass Mountain, Prairie Peak, Roman Nose Mountain, Tyee Mountain, and Saddle Mountain. Panchromatic and color infrared air photography guided sampling within individual balds. The resultant floristic data was manipulated by a Braun-Blanquet...
The western cherry fruit fly, Rhagoletis indifferens
Curran, was studied to determine the suitability of the
sterile insect technique for its control. To obtain
insect material, field collection of maggots is preferred
to sifting of soil or rearing on artificial diet.
The western cherry fruit fly is strictly univoltine;
only...
The seasonality, relationship of temperature and
photoperiod to growth and post-diapause development, and
overwintering behavior of codling moth, Cydia pomonella L.,
(Lepidoptera: Olethreutidae) were studied over a three year
(1986-1989) period. The developmental threshold varied from
a low of 9.66°C for the second instar to a high of 14.23°C
for...