Index Catalog // ScholarsArchive@OSU

The Effects of Host and Pathogen Variation on Infection Dynamics in the Amphibian-Chytrid System

Creator:: Dang, Trang D.
Abstract:: This dissertation uses manipulative experiments to explore amphibian-Bd infection dynamics. Although there has been almost two decades research since the discovery of Bd, many questions still remain regarding what conditions mediate chytridiomycosis virulence. My research shows how certain host and pathogen factors can influence disease virulence. Identifying how host and...
Resource Type:: Dissertation
Full Text:: , e38473. doi:10.1371/journal.pone.0038473. 14 Briggs, C. J., Knapp, R. A. and Vredenburg, V

The role of the transcriptional regulatory protein BCL11B in dental and craniofacial development

Creator:: Kyrylkova, Kateryna
Abstract:: BCL11B is a transcriptional regulatory protein that plays essential roles during mouse embryonic development. BCL11B is expressed and functions in the immune and nervous systems as well as within ectodermal organs. Multiple studies have characterized the roles of BCL11B in T cells, brain, and skin. However, very little is known...
Resource Type:: Dissertation

Examination of the Impact of HIV Stigma and Male Peers on Men’s Communication About HIV Self-Testing and the Role of mHealth in Supporting HIV Self-Testing Within Tanzania

Creator:: Alidina, Zainab
Abstract:: Tanzania has seen a steady decrease in HIV prevalence over the past decade; however, the current HIV prevalence is 4.8% among Tanzanian adults. HIV testing is the first step in the treatment cascade and is key to getting those living with HIV in Tanzania linked to care and reducing their...
Resource Type:: Dissertation

Structure and Dynamics of the Canine (Canis familiaris) Nasal Microbiome

Creator:: Knorr, Elizabeth
Abstract:: The diverse community of bacteria living within and on host organisms, known as the microbiome, has an important role in maintaining host health. Dysbiosis, known as a change in the healthy community of the microbiome, has been associated with a number of diseases across host organisms and body sites including...
Resource Type:: Dissertation
Full Text:: Microbial Diversity in Mice. PLOS ONE 11:e0150502. DOI: 10.1371/journal.pone.0150502. 11. Couch CE

Habitat Use and Ecological Interactions of Invasive Lionfish in the Bahamas

Creator:: Davis, Alexandra C. D.
Abstract:: Invasive species are a growing global economic and ecological problem. Invasive Indo-Pacific lionfish (Pterois spp.) are known to have extreme negative effects on coral-reef communities in the Bahamas, so understating their distribution within and among reefs, what limits their local movements, and the effects they have on native prey species...
Resource Type:: Dissertation
Full Text:: coral reefs. PLoS One 9:1–10. doi: 10.1371/journal.pone.0106229 Barbour AB, Montgomery ML

Host-pathogen Interactions of Respiratory RNA Viruses and the Application of Recombinase Polymerase Amplification for Viral Diagnostics

Creator:: Prescott, Meagan A.
Abstract:: Humans and viral disease are inextricably intertwined. Viral disease plays an immeasurable role in human life, from the disease and economic burden associated with every facet of contending with human viral disease, to managing the consequences of viral disease in organisms important to our food supply, economy, and entertainment. The...
Resource Type:: Dissertation

Novel Extensions and New Applications for Nonparametric Self-Exciting Point Processes

Creator:: Boyd, Peter C.
Abstract:: In this dissertation I will demonstrate a novel application of self-exciting point process models to mass shooting data. I will also introduce two adaptations to the traditional nonparametric Hawkes process modeling framework. One such modification allows for the estimation of the additional productivity introduced by an event that is not...
Resource Type:: Dissertation

The use of omics for disease evaluation in the brains of marine mammals

Creator:: Rosales, Stephanie
Abstract:: Marine mammals are top predators that are essential for the health and function of our oceans. These top predators are often affected by various factors that can be detrimental to their populations. Therefore, there is a need to evaluate undetermined causes of deaths and to better understand known diseases in...
Resource Type:: Dissertation

Bacterial and Host Factors Contributing to Mycobacterium avium subspecies paratuberculosis Persistent Infection

Creator:: Phillips, Ida L.
Abstract:: Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s disease, a chronic granulomatous enteritis that plagues domestic and wild ruminants globally. During the silent stages of Johne’s disease, infected animals intermittently shed bacteria for years prior to clinical diagnosis during advanced disease stages. This strategy allows MAP to...
Resource Type:: Dissertation

Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

Creator:: Joseph, Jayanthi J.
Abstract:: To examine the macrophage response to M. avium, I compared inflammasome and cytosolic sensor expression and activation. My result demonstrated that virulent strains of M. avium (A5 and 104) suppress IL-1β production and induce IFN-β production in macrophages. M. avium mutants deficient at DNA export in the biofilm exhibited reduced...
Resource Type:: Dissertation

ScholarsArchive@OSU

The Effects of Host and Pathogen Variation on Infection Dynamics in the Amphibian-Chytrid System

The role of the transcriptional regulatory protein BCL11B in dental and craniofacial development

Examination of the Impact of HIV Stigma and Male Peers on Men’s Communication About HIV Self-Testing and the Role of mHealth in Supporting HIV Self-Testing Within Tanzania

Structure and Dynamics of the Canine (Canis familiaris) Nasal Microbiome

Habitat Use and Ecological Interactions of Invasive Lionfish in the Bahamas

Host-pathogen Interactions of Respiratory RNA Viruses and the Application of Recombinase Polymerase Amplification for Viral Diagnostics

Novel Extensions and New Applications for Nonparametric Self-Exciting Point Processes

The use of omics for disease evaluation in the brains of marine mammals

Bacterial and Host Factors Contributing to Mycobacterium avium subspecies paratuberculosis Persistent Infection

Characterization of Mycobacterium avium subsp. hominissuis Interactions with Host Macrophages and Multinucleated Giant Cells

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