A model of acute glutamate- and domoate-induced toxicity was developed and characterized in cultured rat cerebellar granule cells (CGCs) using experimental conditions which preserve the voltage-dependency of NMDA receptor function. Glutamate, which is normally non-toxic to CGCs in physiologic media (pH 7.4), was shown to induce a cytotoxic response after...
Human security is a framework related to the stability and sustainability of political, environmental, economical, and socio-cultural areas of concern. Water resources around the world are under increased pressure from increased development, growing populations, pollution, and global climate change. Large-scale dam development while still popular for political and economic development...
The goal of this dissertation was to improve our abilities in acquiring critical in vivo data by establishing embryo-larva zebrafish as an exemplary model to quantitatively evaluate cancer progression. The living environment that encompasses a tumor has a significant effect on how cancer develops, grows and metastasizes. In order to...
Understanding the spiritual worldview of clients is a core element of multicultural competency for mental health professionals. One spiritual and religious population is members of The Church of Jesus Christ of Latter-day Saints and related Latter-day Saint populations. The Book of Mormon is an important sacred text of this population....
Microalgae has been under careful consideration as a sustainable feedstock for renewable fuel recently due to its year round production with high energy yields per unit area, reduced need for arable land, water treatment benefits with nutrient cycling, and minimal competition with the food industry. Despite of all these advantages,...
Chinook salmon, Oncorhynchus tshawytscha, returning to the Yukon River basin and other large river systems in western Alaska have declined dramatically since the late 1990s. This continuing trend has raised concerns over the future status of the returns, and severely impacted commercial and subsistence fisheries within the drainage. Management is...