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Filtering by: Contributor Gonzalez-Montiel, Gisela Resource Type Dissertation

Elucidating the Origins of Trends and Selectivities of Organic Reactions through Computations and Data Analysis Techniques

Creator:

Richardson, H. Camille

Abstract:

In this dissertation, a novel method for analyzing computed transition states (TS) for organic reactions is disclosed. It introduces the use of localization-delocalization matrices as parameters in a linear free energy relationship to determine the transition state interactions responsible for differences in energy between the major and minor TS in...

Resource Type:

Dissertation

Full Text:

going through this with me. Thank you to Joe Harper, Gisela Gonzolez-Montiel, Taisiia Feoktistova
Drug Discovery from Diverse Bacteria – Bioactivity-guided Isolation of Known and New Metabolites

Creator:

Zhu, Chenxi

Abstract:

Exploring bioactive natural products has contributed largely to clinically approved drugs we have been using over the last 100 years. Especially among the anti-infective drugs, around 70% of currently used antibiotics were discovered or derived from microbial secondary metabolites, among them compounds like vancomycin, chloramphenicol, and erythromycin. Facing the unavoidable...

Resource Type:

Dissertation

Full Text:

. Birte Plitzko, Gisela González- Montiel, Mahsa Khoshbakht, and many undergraduate students. I am
Quorum-sensing-controlled public goods in Pseudomonas aeruginosa : regulation and application

Creator:

Mellbye, Brett L.

Abstract:

Cell-to-cell communication by chemical signals, termed quorum sensing (QS), is a common regulatory scheme in the microbial world. Pseudomonas aeruginosa¸ an opportunistic pathogen of burn wounds and cystic fibrosis lungs, uses QS to control the expression of hundreds of genes, particularly those necessary for population level benefits such as biofilm...

Resource Type:

Dissertation

Full Text:

Bacterial Stress Reponses Second Edition, Chapter 20, p. 349-363, ASM Press Edited by Gisela Storz and