Cell signaling under external stimulation is a critical mechanism that governs many biological processes such as cell proliferation, cell migration, and cell apoptosis, etc. For multicellular organisms, the ability to synchronize heterogeneous individual cellular responses through intercellular communication is crucial to maintain normal functionality. However, even though the biological pathways...
Irritable bowel syndrome (IBS) is a prevalent gastrointestinal disorder experienced by 10–15% of the global population, manifesting as chronic abdominal pain, bloating and inconsistent bowel habits. The search for effective treatments remains ongoing. One promising contender in this realm is kappa-casein glycomacropeptide (GMP), a milk-derived peptide. Its potential benefits stem...
Rapid and sensitive detection of stress hormones, such as cortisol and dehydroepiandrosterone (DHEA), can benefit the diagnosis of diseases related to adrenal gland disorders, post-traumatic stress disorders, chronic fatigue syndrome, and more. Stress hormones fluctuate in a circadian rhythm, the highest in the early morning and the lowest at night;...
This work investigates the acoustic velocity of gas-liquid mixtures in vertical, co-current flow in a concentric annulus. Acoustic velocity shows promise as a detection parameter for the presence and amount of gas in a liquid flow because of its high sensitivity to gas void fraction in a gas-liquid mixture. However,...
The gut microbiome has been previously implemented in a number of diseases. Of note is its substantial role in metabolic syndrome, which encapsulates a group of conditions that increase the risk of cardiovascular disease, type 2 diabetes, and stroke. Understanding the causal relationships between the gut microbiome and host processes...
People turn to mass spectrometry to answer some of life’s most important questions. From carbon dating of archeological finds to newborn blood screening tests, mass spectrometry allows us to measure molecules which helps advance our knowledge of life and the world we live in. One area of mass spectrometry that...
Given the recent advancements in the field of pulsar timing pertaining to the detection of a stochastic gravitational wave background (GWB), it is now the perfect time to perform tests of gravity via exploration of the correlation signature between the timing data of pairs of pulsars induced by the polarization...
A dissertation describing the results of a series of greenhouse experiments conducted to better understand phytoremediation in stormwater bioretention systems.
After the 1996 national welfare reform known as the Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA) was enacted with more stringent eligibility and work requirements for the Temporary Assistance for Needy Families (TANF) and the Supplemental Nutrition Assistance Program (SNAP) program, a plethora of analyses have followed assessing the...
The intricate relationship between wildlife health and the quality of their environment is well established, with technological advances increasing our understanding and aiding the unraveling of underlying mechanisms. Large herbivores require forage of sufficient quality to maintain their condition to reproduce and survive, all while warding off parasites and predators...