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Filtering by: Creator Kleywegt, Gerard J. Remove constraint Creator: Kleywegt, Gerard J. Resource Type Dissertation Remove constraint Resource Type: Dissertation

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  • Biophysical analyses of peroxiredoxins and a partner reductase

    Creator:
    Hall, Andrea Renée
    Abstract:
    Peroxiredoxins (Prxs) are dominant peroxide-reducing enzymes with two important roles: they protect all organisms from oxidative damage induced by peroxides, and in eukaryotes, they participate in hydrogen peroxide signaling pathways. This dissertation presents studies aimed at the biophysical characterization of select Prxs and a Prx reductase to elucidate their structure-function...
    Resource Type:
    Dissertation
    Full Text:
    and hemoglobin, awarded to J. C. Kendrew, M. Perutz), there have been 16 Nobel Prizes in chemistry

  • Crystallographic studies of Pyrenophora tritici-repentis ToxA

    Creator:
    Sarma, Ganapathy N.
    Abstract:
    Tan spot of wheat is an economically significant disease caused by the fungal pathogen, Pyrenophora tritici-repentis. Certain races of the fungus secrete Ptr ToxA (ToxA), a 13.2 kDa proteinaceous host-selective toxin that is responsible and sufficient to cause disease in susceptible wheat varieties. Disease symptoms develop only when the ToxA...
    Resource Type:
    Dissertation
    Full Text:
    -wheat interaction. Phytopathology 89, 444-449. 16 6. De Wolf, E. D., Effertz, R. J., Au, S. & Franci

  • Deep learning for robotic exploration

    Creator:
    Caley, Jeffrey A.
    Abstract:
    Emerging applications for robotic data collection include ocean monitoring, emergency response and urban search and rescue. At the core of these applications is a robot's ability to make informed decisions on incomplete data. This dissertation addresses this problem by developing novel techniques for modeling and estimating structured environments using deep...
    Resource Type:
    Dissertation
    Full Text:
    this case, the robot does not update any new cells in the occupancy grid. d,e,f,g,h,i,j) The robot

  • Detection, biosynthesis, and structural investigations of naturally occurring alkynes and other microbial metabolites

    Creator:
    Back, Daniel C.
    Abstract:
    Natural products have long been an important source of resources for humans. Many of these compounds possess unique chemical structures and potent biological properties. By targeting natural products with specific chemical properties, we can gain a better understanding of the roles these compounds play in the environment and their interactions...
    Resource Type:
    Dissertation

  • Domain-Independent Planning for Markov Decision Processes with Factored State and Action Spaces

    Creator:
    Raghavan, Aswin
    Abstract:
    Markov Decision Processes (MDPs) are the de-facto formalism for studying sequential decision making problems with uncertainty, ranging from classical problems such as inventory control and path planning, to more complex problems such as reservoir control under rainfall uncertainty and emergency response optimization for fire and medical emergencies. Most prior research...
    Resource Type:
    Dissertation
    Full Text:
    Improvement (V 0n+1, π)← T (Vn) if ||V 0n+1 − Vn|| ≤ �(1− γ)/2γ return (Vn, π) //Partial Policy Evaluation j

  • Evaluating Transportable Conversion Facilities for a Forest Biomass Supply Chain in the Pacific Northwest, USA

    Creator:
    Berry, Michael D.
    Abstract:
    This dissertation presents an analysis of transportable biomass conversion facility design to evaluate the conceptual and economic viability of a mobile and modular biomass conversion supply chain in the Pacific Northwest, USA. The main goal of this work is to develop a decision support system to more effectively and sustainably...
    Resource Type:
    Dissertation
    Full Text:
    ................................................................211 Appendix J - Glossary

  • Exploring Protein Structure: Seeing the Forest and the Trees

    Creator:
    Brereton, Andrew E.
    Abstract:
    Life on Earth intimately depends on the function of countless proteins. For the majority of studied proteins, function absolutely depends on conformation (i.e. 3-dimensional shape in solution). The exact nature of how a protein goes from an unfolded linear polypeptide chain to an organized folded molecule is still not known,...
    Resource Type:
    Dissertation

  • Immobilized cellooligosaccharides in the study of trichoderma reesei cellobiohydrolases

    Creator:
    Sangseethong, Kunruedee
    Abstract:
    A novel type of model substrates, i.e. immobilized p-aminophenyl-β-D-cellooligosaccharides, was developed and used in the study of exocellulases. The two major cellobiohydrolases from Trichoderma reesei, CBH I and CBH II were used as representative enzymes. p-Aminophenyl derivatives of cellobiose (PAPG₂), cellotriose (PAPG₃), and cellotetraose (PAPG₄) were synthesized from the reaction...
    Resource Type:
    Dissertation
    Full Text:
    ., 1998) J L CeHoOosa Gtucose Figure 2.2 Chemical structure of cellulose residues confers

  • Incorporating Uncertainty in Truckload Relay Network Design

    Creator:
    Mokhtari, Zahra
    Abstract:
    In a relay network for full truckload (TL) transportation, facilities known as relay points (RPs) serve as exchange points where truck drivers can exchange trailers. This would help carriers to assign more regular tours to drivers when compared to the excessively long tours that exist in the traditional Point-to-Point (PtP)...
    Resource Type:
    Dissertation
    Full Text:
    where a load is transported from node i to node j using three RPs. Figure 1: Example of a

  • Learning based methods applied to the MAV control problem

    Creator:
    Salichon, Max
    Abstract:
    This thesis addresses Micro Aerial Vehicle (MAV) control by leveraging learning based techniques to improve robustness of the control system. Applying classical control methods to MAVs is a difficult process due to the complexity of the control laws with fast and highly non-linear dynamics. These methods are mostly based on...
    Resource Type:
    Dissertation