Index Catalog // ScholarsArchive@OSU

Machine Learning for Precision Medicine: Application to Cancer Chemotherapy Response Prediction and Wound Healing Status Assessment

Creator:: Wei, Qi
Abstract:: Ph.D. candidate Qi Wei's thesis consists of two projects: Chemotherapy Project: a study based on the research paper "Predicting chemotherapy response of various cancer types using a variational auto-encoder approach" submitted to the bioRxiv preprint archive and accepted by the BMC bioinformatics; and Wound Monitor Project: implementing and assessing analytics...
Resource Type:: Dissertation
Full Text:: 3.5.3 Time-series measurements of C-reactive protein (CRP), Im- munoglobulin G (IgG) can be integrated

Sandy beach surf zones : what is their role in the early life history of Chinook salmon (Oncorhynchus tshawytscha)?

Creator:: Marin Jarrin, Jose R.
Abstract:: Early life stages of many marine and diadromous fish species use sandy beach surf zones, which occur along >50% of the world's marine coastlines. This extensive habitat can provide juvenile fishes with an abundant supply of potential prey and the ability to hide from predators in its shallow turbid waters....
Resource Type:: Dissertation
Full Text:: fresh water temperature (1.5 to 5.8°C), sea surface temperature (1.2°C) and wave height (0.75 m

Mechanistic studies on Re(V) mediated C-O bond transformations

Creator:: Zhuravlev, Fedor
Abstract:: In situ, reduction of Cp*ReO₃ by PPh₃ to form (Cp*ReO)₂(μ-O)₂ allows catalytic deoxygenation of epoxides, however, conproportionation between Reⱽ and Reⱽᴵᴵ species to form clusters of ((Cp*Re)₃(μ-O)₆}²⁺(ReO₄⁻)2 and new compound {(Cp*Re)₃(μ²-O)₃(μ³-O⁾³ReO₃}⁺(ReO₄⁻) leads to removal of rhenium from the catalytic cycle and loss of activity, The epoxide deoxygenation mediated by (Cp*ReO)₂(μ-O)₂...
Resource Type:: Dissertation
Full Text:: Re(V) MEDIATED C-O BOND TRANSFORMATIONS. CHAPTER 1. GENERAL INTRODUCTION Oxidation of organic and

Molecular characterization of an HIV-1 drug target and antiviral compound development

Creator:: Maselko, Maciej
Abstract:: The Human Immunodeficiency Virus -1 (HIV-1) has been the source of substantial human misery since it was first discovered in the early 1980s. Despite remarkable progress that has been made towards understanding HIV- 1, there is no cure, no vaccine and life-prolonging therapies are beyond the reach of millions in...
Resource Type:: Dissertation
Full Text:: the C-terminal domain of RNA polymerase II which dramatically improves its processivity (Jeang, Xiao

An Investigation into the Functional Properties of the Deafness Causing Protein Otoferlin

Creator:: Manchanda, Aayushi
Abstract:: Otoferlin is a C2-domain, transmembrane protein whose mutated form is responsible for the DFNB9 subtype of prelingual hearing impairment. Mutations in otoferlin cause an autosomal recessive, non-syndromic form of deafness that is characterized by auditory neuropathy/ auditory dissynchrony (AN/AD), meaning that the outer hair cells (OHCs) are normal, and the...
Resource Type:: Dissertation
Full Text:: , and Dr Christiane Loehr for all their helpful suggestions that made my science better. To my BB and

Small mammal and bird abundance in relation to post-fire habitat succession in mountain big sagebrush (Artemisia tridentata ssp. vaseyana) communities

Creator:: Holmes, Aaron L.
Abstract:: Fire is an important disturbance mechanism in big sagebrush (Artemisia tridentata) communities, yet little is known about wildlife population dynamics during post-fire habitat succession. I estimated the abundance of small mammals and birds in relation to fire history in mountain big sagebrush (A.t. spp. vaseyana) communities on the Sheldon National...
Resource Type:: Dissertation
Full Text:: , R. G. Anthony, V. E. Marr and C. M. Duncan. 2008. Winter and early spring bird communities in

The role of copper and its chelation by tetrathiomolybdate in inflammation and atherosclerosis

Creator:: Wei, Hao
Abstract:: Endothelial activation with increased expression of cellular adhesion molecules, chemokines and pro-inflammatory cytokines critically contributes to vascular inflammation and the initiation and progression of atherosclerosis. By affecting redox-sensitive cell signaling pathways and transcription factors, redox-active transition metal ions, such as copper and iron, may play an important role in these...
Resource Type:: Dissertation
Full Text:: committee members, Dr. Joseph Beckman, Dr. Emily Ho, Dr. Walt Ream, and Dr. Christiane Loehr for their

The ascorbic acid requirements of older adolescents

Creator:: Davey, Bessie Louise
Abstract:: The concentration of ascorbic acid in the plasma was determined on four levels of ascorbic acid intake for seven day periods in 1946-47 and on three levels of ascorbic acid intake for ten day periods in 1947-48. The subjects, eight girls and eight boys, were 16 to 19 year old...
Resource Type:: Dissertation
Full Text:: daily ascorbic acid intake and their respective means are given in Tables V-A, V-B, V-C and V-D in the

A synthesis of 6-n-propyl-7-methyltetralin-5-C¹⁴

Creator:: Odell, Norman Raymond
Resource Type:: Dissertation
Full Text:: ~CII:OOH ( C6HsC~C (COOH) 2 ( C6fisC~C(COOC2fts)2I I I c~ ca, cs, IV III901 v 90 70 C61fsC~C II:OOC 2

Some potential mechanisms for finely-tuned regulation of phospholipase C-β isozymes : studies of dimerization and phosphatidylinositol 3,4,5-trisphosphate activation

Creator:: Zhang, Yong
Abstract:: Phospholipase C-β (PLC-β) isozymes are key effectors in G protein-coupled signaling pathways. Prior research suggested that some isoforms of PLC-β may exist and function as dimers, but little is known about dimerization of PLC-β. Data from coimmunoprecipitation assays of differentially-tagged PLC-β constructs and sizeexclusion chromatography of native PLC-β support homodimerization...
Resource Type:: Dissertation
Full Text:: Phospholipase C-β Isozymes: Studies of Dimerization and Phosphatidylinositol 3,4,5-Trisphosphate Activation

ScholarsArchive@OSU

Machine Learning for Precision Medicine: Application to Cancer Chemotherapy Response Prediction and Wound Healing Status Assessment

Sandy beach surf zones : what is their role in the early life history of Chinook salmon (Oncorhynchus tshawytscha)?

Mechanistic studies on Re(V) mediated C-O bond transformations

Molecular characterization of an HIV-1 drug target and antiviral compound development

An Investigation into the Functional Properties of the Deafness Causing Protein Otoferlin

Small mammal and bird abundance in relation to post-fire habitat succession in mountain big sagebrush (Artemisia tridentata ssp. vaseyana) communities

The role of copper and its chelation by tetrathiomolybdate in inflammation and atherosclerosis

The ascorbic acid requirements of older adolescents

A synthesis of 6-n-propyl-7-methyltetralin-5-C¹⁴

Some potential mechanisms for finely-tuned regulation of phospholipase C-β isozymes : studies of dimerization and phosphatidylinositol 3,4,5-trisphosphate activation

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