Under simulated accident conditions, tees in the primary coolant loop of a Pressurized Water Reactor (PWR) can deviate from their original design purpose and become separators that effectively remove core heat sink capacity. This method of primary coolant removal is a phenomelogical subset of phase separation known as liquid entrainment,...
Cystic ovarian disease (COD) is an anovulatory condition in cattle
that afflicts between 6-18% of all dairy cows in the US. Ovulation is
dependent on the plasminogen activator (PA) family of proteases
and protease inhibitor for proteolysis, culminating in follicular rupture.
Failure of the follicle to ovulate suggests an aberration...
Studies of Hawaiian volcanoes contribute valuable insights about Earth processes and mantle evolution, and are fundamental for understanding the construction of the largest volcanoes on terrestrial planets. The pre-shield stage exists in every Hawaiian volcano, but is usually blanketed by high volume tholeiitic lava flows during the main shield stage....
The primary goal of this study is to access the processes that alter primary melts after segregation from a mantle source and ultimately form petrologic Layers 2 and 3 of the Ocean Crust. Mineral, melt inclusion, and whole rock chemical compositions are utilized to further the understanding of 1) the...
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Allison B. Weinsteiger, Author
ACKNOWLEDGEMENTS
I would like to thank Adam Kent and
Diseases caused by parasites are recognized as significant sources of mortality in wild fish populations. I assessed the impacts of multispecies parasitism on a threatened stock of juvenile coho salmon (Oncorhynchus kisutch). A crucial prerequisite to this research was proper identification of parasites, which can be difficult for species lacking...
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Michael L. Kent
Diseases caused by parasites are recognized as significant sources of
Pseudoloma neurophilia is the most common pathogen reported in zebrafish (Danio rerio) research facilities and is an important threat to the zebrafish model. This microsporidian parasite can cause clinical disease, but more importantly is a causative agent of non-protocol induced variation in research. Studies utilizing infected zebrafish, could potentially confound...
Environmental mycobacteria are important opportunistic pathogens for many hosts,
including humans, cattle, and fish. Two well-studied species are Mycobacterium
avium subsp. avium, a significant cause of disseminated bacterial disease in patients
with AIDS, and Mycobacterium avium subsp. paratuberculosis, the cause of Johne’s
disease in cattle. Many other species that are...
Zebrafish, Danio rerio, are widely used as vertebrate research organisms yet little is know about their responses to husbandry stressors. This dissertation examined the whole-body cortisol responses of zebrafish to husbandry stress. Additionally, the effects of stress on the susceptibility to mycobacteriosis and microsporidiosis (Pseudoloma neurophilia) were determined including effects...
Semi-volatile trace metals like Li, Cu, Mo, Sn, In, and Pb have the potential to track mobility of a volatile phase in volcanic systems. In this dissertation four studies are presented that either directly investigate or are motivated by observations of trace metal behavior in volcanic systems. A common tool...
The microsporidian parasite, Pseudoloma neurophilia, is the most commonly diagnosed infectious disease in laboratory populations of the zebrafish, Danio rerio. Infections by P. neurophilia are generally subclinical, however, they can become acute either incidentally or due to experimental immune suppression. Non-protocol induced variation can confound results in laboratory experiments using...