Index Catalog // ScholarsArchive@OSU

Chemical and biological approaches to identify vertebrate tissue regeneration pathways

Creator:: Sengupta, Sumitra
Abstract:: Numerous human conditions would be improved if therapies to encourage tissue regeneration were available. The goal of regenerative medicine is to encourage the body's intrinsic ability to repair and restore tissues lost by disease, injury or aging. While certain vertebrates have the inherent capacity to regenerate, mammals do not. To...
Resource Type:: Dissertation
Full Text:: and spinal cord. The organization of the genome and the genetic pathways involved with signal

Pseudoloma neurophilia in the Zebrafish (Danio rerio) : Consequences of Infection on Neurobehavioral and Biomedical Research using a Burgeoning Model Organism

Creator:: Spagnoli, Sean
Abstract:: Since its inception as a laboratory animal in the early 1970s, the zebrafish has proven itself a rising star in the world of comparative biomedical sciences due to its short generation time, ease of care, external fertilization, and transparent larvae. In a very few decades, the zebrafish has been utilized...
Resource Type:: Dissertation
Full Text:: Health Sciences presented on May 27, 2016 Title: Pseudoloma neurophilia in the Zebrafish (Danio

Establishing Larval Zebrafish as an In Vivo Model Organism for Characterizing the Roles of Otoferlin, a Sensory Hair Cell Protein Essential for Hearing

Creator:: Chatterjee, Paroma
Abstract:: Auditory defects and disorders are prevalent at all ages and affect 8% of the population in developed nations including newborns and children. Congenital hearing loss is the most common birth defect and it is estimated that 1 in 1000 children are affected by deafness at birth or before the onset...
Resource Type:: Dissertation
Full Text:: associated symptoms. More than two- thirds of non-syndromic hearing loss cases are of genetic origin, with

Evaluation of zebrafish (Brachydanio rerio) as a model for carcinogenesis

Creator:: Tsai, Hsi-Wen
Abstract:: Zebrafish (Brachydanio rerio) are small, freshwater teleost fishes in the family Cyprinidae, the true minnows. They are native to the tropical latitudes of India, but have become widespread through their use as aquarium fish and as models for several branches of biological research. Their ease of rearing, short generation time,...
Resource Type:: Dissertation
Full Text:: 49 CHAPTER 3: THE CARCINOGENICITY OF DIETARY AFLATOXIN B, TO ZEBRAFISH {Brachydanio danio) AND

Husbandry stress of Zebrafish, Danio rerio

Creator:: Ramsay, Jennifer Mara
Abstract:: Zebrafish, Danio rerio, are widely used as vertebrate research organisms yet little is know about their responses to husbandry stressors. This dissertation examined the whole-body cortisol responses of zebrafish to husbandry stress. Additionally, the effects of stress on the susceptibility to mycobacteriosis and microsporidiosis (Pseudoloma neurophilia) were determined including effects...
Resource Type:: Dissertation
Full Text:: Science presented on December 17, 2008 Title: Husbandry Stress of Zebrafish, Danio rerio Abstract

Aflatoxin B₁ metabolism, CYP1A induction, and the influence of CYP1A induction on aflatoxin B₁ metabolism in zebrafish

Creator:: Troxel, Claudia McLaughlin
Resource Type:: Dissertation
Full Text:: AFLATOXIN B1 METABOLISM AND HEPATIC DNA ADDUCTION IN ZEBRAFISH (Danio rerio) 28 Abstract 29

Pseudoloma neurophilia : progression of infection and transmission characteristics of a microsporidian parasite in a model vertebrate, Danio rerio

Creator:: Sanders, Justin L.
Abstract:: The microsporidian parasite, Pseudoloma neurophilia, is the most commonly diagnosed infectious disease in laboratory populations of the zebrafish, Danio rerio. Infections by P. neurophilia are generally subclinical, however, they can become acute either incidentally or due to experimental immune suppression. Non-protocol induced variation can confound results in laboratory experiments using...
Resource Type:: Dissertation
Full Text:: . 53, 126–134. De Kinkelin, P. (1980). Occurrence of a microsporidian infection in zebra danio

Consequences of miRNA misregulation on embryonic development and aging

Creator:: Franzosa, Jill A.
Abstract:: microRNAs (miRNAs), ~21-24 nucleotide-long RNAs that post-transcriptionally regulate gene expression, have rapidly become one of the most extensively studied mechanisms of the past decade. Since their discovery as temporal regulators of post-embryonic development in C. elegans, miRNAs have been functionally implicated in almost every cellular process investigated to date. miRNAs...
Resource Type:: Dissertation
Full Text:: the many genetic and biochemical processes which contribute to stem cell aging (i.e. telomerase

Initial in vitro and in vivo Characterization of the Membrane Trafficking Protein Fer1L6

Creator:: Wolk, Chelsea
Abstract:: A fundamental difference between prokaryotic and eukaryotic cells is the presence of membrane bound organelles in eukaryotes. The dynamics of membrane trafficking within the cell are responsible for everything from intercellular communication and cell homeostasis, to mitosis, cell migration, and differentiation. These processes require exocytosis and compensatory endocytosis, often working...
Resource Type:: Dissertation
Full Text:: . Reverse genetic techniques were used to elucidate a possible functional role of Fer1L6 in the model

Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish

Creator:: Haggard, Derik
Abstract:: There are more than 87,000 chemicals in current use with little to no toxicity information available. Assessing such a large number of chemicals using traditional methods would take an unreasonable amount of time and money, and require the use a large number of animals. The incorporation of high-throughput in vivo...
Resource Type:: Dissertation
Full Text:: et al., 2003; Cox and Goessling, 2015). Humans and zebrafish share ~70% of genetic homology and ~82

ScholarsArchive@OSU

Chemical and biological approaches to identify vertebrate tissue regeneration pathways

Pseudoloma neurophilia in the Zebrafish (Danio rerio) : Consequences of Infection on Neurobehavioral and Biomedical Research using a Burgeoning Model Organism

Establishing Larval Zebrafish as an In Vivo Model Organism for Characterizing the Roles of Otoferlin, a Sensory Hair Cell Protein Essential for Hearing

Evaluation of zebrafish (Brachydanio rerio) as a model for carcinogenesis

Husbandry stress of Zebrafish, Danio rerio

Aflatoxin B₁ metabolism, CYP1A induction, and the influence of CYP1A induction on aflatoxin B₁ metabolism in zebrafish

Pseudoloma neurophilia : progression of infection and transmission characteristics of a microsporidian parasite in a model vertebrate, Danio rerio

Consequences of miRNA misregulation on embryonic development and aging

Initial in vitro and in vivo Characterization of the Membrane Trafficking Protein Fer1L6

Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish

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