Microfluidics is an evolving field that focuses on the manipulation of small fluid volumes. Because of its micron-sized features, it is the basis for many lab-on-chip and point-of-care diagnostic devices. The devices are predominantly molded from polydimethylsiloxane (PDMS); however, production is a multi-hour or multi-day process that typically requires clean...
Cell counting is a key tool used in biological and clinical laboratories, but at present, commercial cell counters are large and expensive. CMOS technology is a promising platform for creating small, low-cost sensors but currently lacks a robust method of directly interfacing these sensors with the microfluidic networks needed for...
Thermoelectric generators (TEGs) have gained much popularity in the search for alternatives to clean sources to harvest energy. Given their capability to harness an electric potential given a temperature differential across their opposing faces, and the foreseeable prevalence of naturally and/or commonly occurring temperature gradients in multiple applications, TEGs are...
Nowadays, woody biomass is becoming increasingly significant because of its renewability and biodegradability. Lots of opportunities have been found to use excessive biological resources to derive products as diverse as fuels, heat, electricity, chemicals, food, clothing, paper, and much more. As such, biomass plays an important role in meeting demands...
To assess the conversion and embedment of yttrium nitrate to yttrium oxide using selective laser melting, a thermodynamic approach for laser power and scan speed predictions on surface temperature, recoil pressure, and resulting track morphology window are employed. Inkjet printing is used to deposit the liquid film of yttrium nitrate...
Immature T cells, known as thymocytes, undergo development through successive stages in the thymus and the periphery to become functional mature T cells. These stages are regulated by sequence specific transcription factors (SSTFs). Two such SSTFs, BCL11B and TCF-1, are both known master regulators of thymopoiesis, which is also known...
Flame retardants are in many home products including couches, chairs, and electronics. The most commonly used flame retardants contained polybrominated diphenyl ethers (PBDEs) until 2004, when the majority of these chemicals were phased out. PBDEs were found to be persistent, bioaccumulative, and toxic to both humans and the environment. Organophosphate...
The action of pendant, polyethylene oxide (PEO) brush layers as nonfouling coatings for
biomedical materials is well understood. However progress toward clinical application of stable, high density PEO coatings has historically been impeded by the lack of cost effective, noninvasive methods for their preparation. Triblock polymers featuring a hydrophobic, polypropylene...
PRC2 (Polycomb Repressive Complex 2) mediated gene silencing plays an important role in cell differentiation, stem cell plasticity, and tumor suppression. In fungi, it is also involved in pathogenicity. The catalytic subunit, KMT6, trimethylates lysine 27 on histone h3 (H3K27me3) at loci targeted for silencing. In animals, PRC1 and PRC2...
On a daily basis, employees in the service industry manage their emotional and physical displays, both to their coworkers and customers. Whether this management is for personal gain or organizational requirement, these attempts to manage other’s impressions can have important personal effects. Specifically, when managing emotional displays to customers, there...