Index Catalog // ScholarsArchive@OSU

The Effect of Riluzole on P2X7 and EAAT2 Expression by Inducible Neural Progenitor Cell (iNPC)-derived Astrocytes

Creator:: Sy, Kevin
Abstract:: Although it is the first drug approved for usage to treat amyotrophic lateral sclerosis (ALS), riluzole’s mechanism of action is unknown and its therapeutic quality is hampered by its relatively short window of effectiveness. P2X7 is a purine receptor found in astrocytes and other cells, which increases calcium concentrations within...
Resource Type:: Honors College Thesis
Full Text:: c-Myc-hEAAT2, EAAT2 levels rose slightly over the course of the disease, rather than decreasing

Addressing ALS: Corroborating the Methodology of Studying the P2X7R Complex

Creator:: Veytsman, Edward Y.
Abstract:: Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of motor neurons in the motor cortex and spinal cord. Recent evidence suggests that the purine receptor P2X7 (P2X7R) plays a central role in the pathology of ALS. Previous research indicates that P2X7R activation by oxidatively modified heat shock protein 90...
Resource Type:: Honors College Thesis
Full Text:: was used to make a DMEM mixture with 10 μg/mL polybrene. The frozen virus was thawed at 37oC

Stand Structure of Old Growth Dry Mixed Conifer Forests in the Deschutes and Ochoco National Forests

Creator:: Merschel, Andrew G.
Abstract:: Old-growth dry-mixed conifer forests are valued as habitats for late seral forest species, for the ecosystem services and landscape diversity they provide, and for their aesthetic appeal. The structure of these forests has been heavily altered by historic logging of overstory ponderosa pine and Douglas-fir. Additionally, changes in fire regime...
Resource Type:: Honors College Thesis
Full Text:: THE THESIS OF Andrew G. Merschel for the degree of Honors Baccalaureate of Science in Natural

Understanding polycyclic aromatic hydrocarbon (PAH) toxicity and inflammation in human bronchial epithelial cells

Creator:: Valdez, Teresa
Abstract:: There is increased emphasis on understanding cumulative risk from the combined effects of chemical and non-chemical stressors as it relates to public health. Recent animal studies have identified pulmonary inflammation as a possible modifier and risk factor for chemical toxicity in the lung after exposure to inhaled pollutants; however, little...
Resource Type:: Honors College Thesis
Full Text:: Susan C. Tilton There is increased emphasis on understanding cumulative risk from the combined

Impact of Vitamin E Deficiency on Hepatic Gene Expression of CRAL_TRIO Family Proteins in a Premier Vertebrate Animal Model

Creator:: Watt, Alexander T.
Abstract:: Vitamin E (vitE) is a group of lipid-soluble antioxidants- of which alpha-tocopherol is the most biologically active and only form considered to be an essential nutrient. Through preferential binding and trafficking, the alpha-tocopherol transfer protein (α-TTP) regulates the concentration of vitE in the body. The impact of vitE deficiency on...
Resource Type:: Honors College Thesis
Full Text:: 1 2 3 4 CRAL-TRIO Gene E - M e a n F o ld C h a n g e (2 -  c t ) * gpx4a

Role of Nitrated Hsp90 in Schwannoma Cell Survival

Creator:: Kim, Sharon R.
Abstract:: Neurofibromatosis Type 2 (NF2) is a genetic tumor disorder caused by mutations that inactivate the gene coding for the Merlin tumor suppressor. Patients with NF2 develop multiple tumors throughout the nervous system, mainly schwannomas, for which there is no cure or effective treatment. In NF2, redox signaling and oxidative stress...
Resource Type:: Honors College Thesis
Full Text:: -80 °C. A Lowry assay was performed in a 96-well microplate to quantify protein concentration. 30 μg

Hi-C genome assembly of the ectomycorrhizal fungus Rhizopogon salebrosus

Creator:: Har, Skyler
Abstract:: Rhizopogon salebrosus is an abundant ectomycorrhizal fungus common throughout Western North America that forms mutualistic partnerships with Pinus species. Studied for its systematics, use in sapling nurseries, post-fire seedling establishment, and unique evolutionary history, R. salebrosus holds many secrets within its genome. This thesis aims to characterize the mating system,...
Resource Type:: Honors College Thesis
Full Text:: -closed assembly. A C G T N GC GC_stdev 0.2559 0.2444 0.2439 0.2558 0.0022 0.4883 0.0012

Janus-Type Wicking Microfluidic Devices for Separation and Collection of Plasma from Blood

Creator:: Unitan, Linus J.
Abstract:: A simple Janus-type membrane-based wicking microfluidic device fabricated on a polycaprolactone-filled glass microfiber membrane enables separation and collection of blood plasma or serum from whole blood. This device bridges the wicking and cut-capillary-based solution transport mechanisms in a single membrane. The initial portion of the device is fabricated using selective...
Resource Type:: Honors College Thesis
Full Text:: ). (9) Bandara, G. C.; Heist, C. A.; Remcho, V. T. Patterned Polycaprolactone

Using The MPA Guide to Better Understand Global Marine Conservation Efforts

Creator:: McArthur, Madeleine G.
Abstract:: Across the globe, Marine Protected Areas (MPAs) have been established to protect biodiversity, sustain fisheries, and preserve cultural resources. However, there exist broad differences among MPAs with respect to their establishment stage and protective regulations, making it difficult to quantify how much ocean protection is actually occurring. This thesis utilizes...
Resource Type:: Honors College Thesis
Full Text:: Expansion 1,146,120 Highly Protected 2c Midway Atoll Special Management Area 492 Highly Protected

Evaluating the mixed species feeding opportunities provided by foraging humpback whales (Megaptera novaeangliae) across ocean ecosystems

Creator:: Ellett, Lindsey G.
Abstract:: Group foraging occurs across many ecosystems and taxa, and benefits some or all individuals in the group by optimizing feeding efficiency. The beater theory describes when individual “beaters” benefit other group members by herding prey into more accessible areas. Humpback whales feed on a variety of small patchy prey, and...
Resource Type:: Honors College Thesis
Full Text:: , (b) using a bubble net to capture anchovy prey, (c) exhibiting bird and sea lion group foraging

ScholarsArchive@OSU

The Effect of Riluzole on P2X7 and EAAT2 Expression by Inducible Neural Progenitor Cell (iNPC)-derived Astrocytes

Addressing ALS: Corroborating the Methodology of Studying the P2X7R Complex

Stand Structure of Old Growth Dry Mixed Conifer Forests in the Deschutes and Ochoco National Forests

Understanding polycyclic aromatic hydrocarbon (PAH) toxicity and inflammation in human bronchial epithelial cells

Impact of Vitamin E Deficiency on Hepatic Gene Expression of CRAL_TRIO Family Proteins in a Premier Vertebrate Animal Model

Role of Nitrated Hsp90 in Schwannoma Cell Survival

Hi-C genome assembly of the ectomycorrhizal fungus Rhizopogon salebrosus

Janus-Type Wicking Microfluidic Devices for Separation and Collection of Plasma from Blood

Using The MPA Guide to Better Understand Global Marine Conservation Efforts

Evaluating the mixed species feeding opportunities provided by foraging humpback whales (Megaptera novaeangliae) across ocean ecosystems

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