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Filtering by: Subject Antibiotics -- Synthesis Resource Type Masters Thesis

Biosynthetic studies of fungal diterpene antibiotics

Creator:

Yao, Qingmei

Abstract:

The isoprenoid pathway is one of the major biosynthetic pathways of secondary metabolites. Isoprenoids with a C₂₀ skeleton are known as diterpenoids and are derived from the common precursor, geranylgeranyl diphosphate (GGPP). This dissertation describes approaches to discover the diterpene synthase enzymes which provide the backbone structures for pleuromutilin and...

Resource Type:

Masters Thesis

Full Text:

Pleurotus passeckerianus Pilat Antibiotic compounds………………………………………… 31 Introduction to
Formation and modification of enduracididine, a nonproteinogenic amino acid

Creator:

Tan, Ying

Abstract:

Molecular genetic and enzymological techniques have been employed to study antibiotic biosynthesis. In this thesis, we studied the formation and modification of the nonproteinogenic amino acid enduracididine (End), which exists in two important antibiotics, mannopeptimycins (MPPs) and enduracidin. Sequence analysis of the MPP gene cluster revealed that the product of...

Resource Type:

Masters Thesis

Full Text:

Molecular genetic and enzymological techniques have been employed to study antibiotic biosynthesis. In
The synthesis of macrolactones from [omega]-hydroxyacyl xanthates

Creator:

Akella, Annapoorna

Resource Type:

Masters Thesis

Full Text:

within the molecule. 0 0 O OH 1 2 Examples of 14-membered macrolides are the antibiotic substances
Syntheses of labeled putative intermediates in acivicin biosynthesis

Creator:

Jiang, Nan

Resource Type:

Masters Thesis

Full Text:

of Acivicin Acivicin is an antitumor antibiotic. It also has antifungal activity. Its antibacterial