Index Catalog // ScholarsArchive@OSU

In vivo assessment of nanomaterial-induced toxicity using embryonic zebrafish

Creator:: Usenko, Crystal Y.
Abstract:: Due to their unique physical, chemical, and magnetic properties, nanomaterials have great potential for industrial development. There is a pressing need to develop rapid whole animal-based testing assays to assess the potential toxicity of engineered nanomaterials. To meet this challenge the embryonic zebrafish model was employed to determine the toxicity...
Resource Type:: Masters Thesis
Full Text:: approved: _____________________________________________________________ Robert L. Tanguay Due to

Profiling Zebrafish Developmental Responses to E-Cigarette Flavor Mixtures

Creator:: Holden, Laura, L.
Abstract:: Since 2007, electronic cigarette (e-cigarette) sales in the U.S. have surpassed those of tobacco cigarettes. This is due, in part, to manufacturer’s claims that they are a safer alternative to tobacco cigarettes. However, formaldehyde, acrolein, and diacetyl have been detected in e-cigarettes and public knowledge of e-cigarette composition and potential...
Resource Type:: Masters Thesis
Full Text:: approved: ______________________________________________________ Robert L. Tanguay Since 2007

Assessment of fluorinated chemicals (FCs) on developmental toxicity in embryonic zebrafish

Creator:: Duong, Lisa
Abstract:: Fluorinated chemicals (FCs) have been used since the 1950s in many industrial and commercial applications because of their unique properties such as chemical inertness, resistance to heat and their ability to repel water and oils. Concerns regarding potential environmental or human health risk from FCs exposure have emerged due to...
Resource Type:: Masters Thesis
Full Text:: : __________________________________________________________________________ Robert L. Tanguay Fluorinated chemicals (FCs) have been used since the 1950s in many

Automated manipulation of zebrafish embryos for high-throughput toxicology screening of nanomaterials

Creator:: Mandrell, David
Abstract:: The field of nanotechnology has been rapidly developing new materials. These materials have become incorporated into consumer products and the environment after only minimal assessment of their effects on human health or the environment. The toxicity of these new nanomaterials remains unknown due to the unpredictable nature of the core...
Resource Type:: Masters Thesis
Full Text:: to thank Dr. Robert Tanguay for giving me the opportunity to work on a project that I have truly

The use of natural plant extracts as a feed additive to prevent laminitis in lactating dairy cows

Creator:: Pierson, Miranda L.
Abstract:: Two experiments were conducted looking at both acute and sub-acute laminitis. An acute nutritional induction model was used to examine whether blood profiles and gene expression are similar to other studies conducted using an endotoxin induction model. Twelve sheep were randomly assigned to three treatment groups which were control, 4-hour...
Resource Type:: Masters Thesis
Full Text:: Mike Gamroth and Dr. Robert Tanguay for joining my graduate committee on such short notice. I would

Embryogenesis is dependent upon 12-lipoxygenase, 5-lipoxygenase, and alpha-tocopherol to modulate polyunsaturated fatty acid status and the production of oxidized fatty acids in zebrafish, Embryogenesis is dependent upon 12-lipoxygenase, 5-lipoxygenase, and α-tocopherol to modulate polyunsaturated fatty acid status and the production of oxidized fatty acids in zebrafish

Creator:: Lebold, Katherine M.
Abstract:: Arachidonic acid (ARA) and docosahexaenoic acid (DHA) are polyunsaturated fatty acids required for proper embryonic development, specifically neurodevelopment. However, little is known regarding their conversion to other metabolites during embryogenesis. The oxidation of ARA gives rise to the biologically active eicosanoids and the oxidation of DHA gives rise to the...
Resource Type:: Masters Thesis
Full Text:: interpretation. Robert L. Tanguay contributed to study design and data interpretation. Maret G. Traber was

Evaluation of polymer modified asphalt in hot mix pavements

Creator:: Ifft, Charles
Abstract:: Polymer modified asphalts have recently been the focus of much attention in the U.S. due to claims that polymer additives will lengthen the life of an asphalt pavement. Much of the published research on this topic has been concentrated on the effects of polymer modifiers on binder and mixture properties....
Resource Type:: Masters Thesis
Full Text:: , & Tanguay (French Central Public Works) Krivohlavek Fleckenstein & Allen Collins (Shell Development Co

Spherical Au Nanoparticle Interaction with Lipid Monolayers Probed with Sum Frequency Generation Spectroscopy

Creator:: Faase, Ryan A.
Abstract:: Nanoparticles have become more prevalent from their use in sunscreen to antimicrobial agents in socks. In light of these applications, gaining a fundamental understanding of how NPs interact with humans is crucial for their future. Specifically, how cells interact with NPs and what factors drive the modes of cellular uptake....
Resource Type:: Masters Thesis
Full Text:: . M.; Hutchison, J. E.; Tanguay, R. L., Surface functionalities of gold nanoparticles impact

Intestinal hyperplasia and neoplasms in zebrafish (Danio rerio)

Creator:: Paquette, Colleen Elizabeth
Abstract:: Zebrafish (Danio rerio) have become an increasingly important model organism for cancer research. There are several cancer models in which neoplasms are induced chemically or genetically. However, spontaneous (unknown etiology) neoplasms are rather common in zebrafish, particularly in older fish. For over a decade, spontaneous intestinal neoplasia and preneoplastic intestinal...
Resource Type:: Masters Thesis
Full Text:: retrospective study in Chapter 2. Robert L. Tanguay provided materials for that same diet study. Karen

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

Creator:: Norby, Tyler S.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are significant pollutants in aquatic environments. Many are carcinogenic and lead to DNA fragmentation and adduct formation in marine and freshwater organisms. Previous research demonstrates that rainbow trout (Oncorhynchus mykiss) compensate to long-term PAH dietary exposures and reduce the DNA damage. The aim of this study...
Resource Type:: Masters Thesis
Full Text:: expensive, so this was most appreciated. Also, thanks go out to Dr. Robert Tanguay and the staff of SARL

ScholarsArchive@OSU

In vivo assessment of nanomaterial-induced toxicity using embryonic zebrafish

Profiling Zebrafish Developmental Responses to E-Cigarette Flavor Mixtures

Assessment of fluorinated chemicals (FCs) on developmental toxicity in embryonic zebrafish

Automated manipulation of zebrafish embryos for high-throughput toxicology screening of nanomaterials

The use of natural plant extracts as a feed additive to prevent laminitis in lactating dairy cows

Evaluation of polymer modified asphalt in hot mix pavements

Spherical Au Nanoparticle Interaction with Lipid Monolayers Probed with Sum Frequency Generation Spectroscopy

Intestinal hyperplasia and neoplasms in zebrafish (Danio rerio)

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

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