Dibenzo[def,p]chrysene (DBC) is a highly potent, but less prevalent, environmental carcinogen belonging to a class of compounds known as Polycyclic Aromatic Hydrocarbons (PAHs). They are highly ubiquitous and arise as a byproduct of natural and anthropogenic combustion processes. Previous studies have documented carcinogenic effects upon in utero exposure of PAHs....
Dibenzo[def,p]chrysene (DBC) is a polycyclic aromatic hydrocarbon (PAH) and an IARC classified 2A probable human carcinogen. Mouse progeny transplacentally exposed to DBC have been shown to develop lung and liver tumors, with liver tumors developing predominantly in males later in life. Sulforaphane (SFN) is an isothiocyanate that plays a crucial...
Vitamin D sufficiency supports cardiovascular health and lower cancer risk. Rates of vitamin D insufficiency vary by racial/ethnic group, in part because skin pigment limits sunlight penetration. However race/ethnicity is an unreliable marker of vitamin D deficiency, given individual differences in skin pigment, or phototype, and other characteristics. Clarifying associations...
Seasonal Affective Disorder (SAD) is a mood disorder that is characterized by depressive symptoms that onset and remit at the same times each year. Whereas few people (about 1%) experience problems severe enough to be labeled SAD, many people (estimates range from 30%-90%) may experience mild to moderate changes in...
Objective: In 2018, suicide was the leading cause of death for individuals between the ages of 10-24 in Oregon (OHA, 2019) and was the second leading cause of death for this age range in 2020 (OHA, 2021). In 2019, 12% of Black high school students reported a suicide attempt in...
Any interaction with another person requires some judgement of their characteristics from a short amount of time. Each day a person can interact with many individuals and quick judgments have to be made in each situation to decide how to act or react. This means a person can make hundreds...
Objective: Alcohol and cannabis use and co-use among college students is prevalent in the United States (Bravo et al., 2021). These substances have been linked to poor collegiate academic performance in past research. The present study examines varying levels of single-substance alcohol use and alcohol and cannabis co-use in their...
Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (BP), are environmental pollutants linked to increased disease susceptibilities. Alpha-Tocopherol (aT) supplementation decreases BP-DNA adducts in smokers, particularly women; but the mechanism is unknown. To test the hypothesis that aT protection from BP exposure is gender-dependent, male and female rats received 7 daily subcutaneous...