Index Catalog // ScholarsArchive@OSU

Immunohistochemical characterization of melanomas in bigenic mice containing activated Cdk4 and keratinocyte specific ablation of Retinoid-X-Receptor alpha (RXRα) protein With international consideration of Differences in Societal and Behavioral Attitudes toward Skin Cancer between Japanese American and Japanese

Creator:: Nguyen, Vananh M.
Abstract:: OVERVIEW OF INTRODUCTION - This is a combined thesis for both disciplines of BioResource Research (BRR)Interdisciplinary and International Degree (ID) Programs OSU. The first chapter encompasses the BRR research, which is a preliminary study utilizing immunohistochemical method to characterize melanomas in bigenic mice with activated Cdk4 protein and Retinoid-X-Receptor α...
Resource Type:: Presentation and Undergraduate Thesis
Full Text:: __________________ Dr. Katharine G. Field, Bioresource Research Director Date

Developing Trap and Kill Technologies to Improve Management of the Western Spotted Cucumber Beetle (Diabrotica undecimpunctata undecimpunctata) and the Western Striped Cucumber Beetle (Acalymma trivittatum)

Creator:: Alderman, Katie
Abstract:: The western spotted cucumber beetle (Diabrotica undecimpunctata undecimpunctata) and the western striped cucumber beetle (Acalymma trivittatum) are pests of many crops, including vegetable, fruit, and nursery crops. Pesticides are commonly used to control this pest. Trap and kill technologies are under development as use in an alternative control for cucumber...
Resource Type:: Undergraduate Thesis and Presentation

Vegetative effects of RNAi-suppression of the poplar homolog of LEAFY in the field

Creator:: Jacobson, Jeremy
Abstract:: Due to public and regulatory restrictions, genetic containment technology is critical for research and development of transgenic trees in forestry. A multi-year field trial demonstrated that the RNAi-LFY construct successfully induces sexual sterility in 6K10 poplar (Populus alba) without visible effects on vegetative development. However, its limited number of replicates...
Resource Type:: Undergraduate Thesis and Presentation
Full Text:: season, when the trees were an average of 1.7 m in height. Due to transplant shock and deer grazing

United States Turtle Mapping Project with a Focus on Western Pond Turtle and Painted Turtle, United States Turtle Mapping Project with a Focus on the Western Pond Turtle (Actinemys marmorata) and the Painted Turtle (Chrysemys picta)

Creator:: Barela, Kimberly L.
Abstract:: We compiled Western Pond Turtle (Actinemys marmorata) and Painted Turtle (Chrysemys picta) locations in northwestern North America, consolidating data from multiple sources including nine U.S. State and Canadian Provincial jurisdictions. We assessed numbers of discrete locations, and analyzed distribution patterns temporally and spatially. Western Pond Turtle observation records ranged from...
Resource Type:: Undergraduate Thesis and Presentation

Mycobacterium tuberculosis Selective Adenosine Kinase Nucleoside Polymers for Inhalation Therapy

Creator:: Snow, Erika
Abstract:: Respiratory illnesses caused by both viral and bacterial infection are serious issues for global healthcare providers. With the emergence of new, drug-resistant forms of these diseases, innovative drugs and treatment therapies are needed. M tuberculosis is an infection that affects a large portion of the world’s population each year. Aerosol...
Resource Type:: Presentation and Undergraduate Thesis

Method development for extraction and purification of dermal RNA from FVB/Nmice treated with environmental PAH mixtures

Creator:: Larkin, Andrew, Siddens, Lisbeth, and Krueger, Sharon
Abstract:: Epidermal RNA samples from FVB/N mice treated with PAH standards and environmental PAH mixtures were harvested and purified using Trizol extraction and RNeasy mini prep kit purification. Epidermal RNA integrity was low (RIN mean 3.5), indicating significant RNA degradation and the need to modify handling, collection, and processing of skin...
Resource Type:: Undergraduate Thesis and Presentation

Combinational Effects of Retinoid-X-Receptor α (RXRα) Ablation with Oncogenic Mutations Cdk4[Superscript R24C/R24C] or N-Ras[Superscript Q61K/Q61K] after Ultraviolet Radiation Induced Melanoma Development, Combinational Effects of Retinoid-X-Receptor α (RXRα) Ablation with Oncogenic Mutations Cdk4R24C/R24C or N-RasQ61K/Q61K after Ultraviolet Radiation Induced Melanoma Development

Creator:: Sherman, Anna
Abstract:: Summary Recent research has identified Retinoid-X-Receptorα (RXRα), a nuclear receptor involved in ligand mediated transcription, as having a protective function against the malignant transformation of melanocytes after treatment with chemical carcinogens. This study used mice selectively lacking keratinocytic RXRα in combination with an oncogenic mutation, either Cdk4[Superscript R24C/R24C] or N-Ras[Superscript...
Resource Type:: Presentation and Undergraduate Thesis
Full Text:: ________________________________________ _______________ Katharine G. Field, BRR Director

Inhibition of α-Amylase and α-Glucosidase by Bioflavonoids

Creator:: Griffith, Anneke M. (Tucker)
Abstract:: Various flavonoid-rich plant extracts have shown efficacy in the treatment of diabetes. Although it is often assumed that dietary flavonoids exert biological antioxidant effects, it is possible that the observed effects work in carbohydrate metabolism. In this study we evaluated the effect of catechins and catechin containing extracts on α-amylase...
Resource Type:: Presentation and Honors College Thesis
Full Text:: i AN ABSTRACT OF THE THESIS OF Anneke M. (Tucker

Effects of Perfluorinated Compounds on GnRH Gene Expression in vitro

Creator:: Bathke, Rebecca E.
Abstract:: Perfluorinated chemicals have been widely used in industry for their superior surfactant qualities. Because of their widespread usage and resistance to photolytic and biodegradation mechanisms, as well as their ability to undergo long-range atmospheric transport, these compounds have become ubiquitous in the world-wide water supplies. Of particular interest are perfluorooctanoic...
Resource Type:: Undergraduate Thesis and Presentation

Immunohistochemistry Studies of Tumor Necrosis Factor Αlpha and Interferon Gamma Expression in Pseudocapillaria tomentosa Infected and Uninfected Zebrafish

Creator:: Lo, Lalee C.
Abstract:: Tumor necrosis factor alpha (TNF α) and interferon gamma (IFN γ) were initially recognized as inflammatory mediators produced by immune cells in response to infectious agents or foreign material. (1,5) However, over the past decade much research in mammalian species has indicated that these proteins also play key roles in...
Resource Type:: Presentation and Undergraduate Thesis
Full Text:: _________________________________ _______________ Katharine G. Field, BRR Director

ScholarsArchive@OSU

Developing Trap and Kill Technologies to Improve Management of the Western Spotted Cucumber Beetle (Diabrotica undecimpunctata undecimpunctata) and the Western Striped Cucumber Beetle (Acalymma trivittatum)

Vegetative effects of RNAi-suppression of the poplar homolog of LEAFY in the field

United States Turtle Mapping Project with a Focus on Western Pond Turtle and Painted Turtle, United States Turtle Mapping Project with a Focus on the Western Pond Turtle (Actinemys marmorata) and the Painted Turtle (Chrysemys picta)

Mycobacterium tuberculosis Selective Adenosine Kinase Nucleoside Polymers for Inhalation Therapy

Method development for extraction and purification of dermal RNA from FVB/Nmice treated with environmental PAH mixtures

Inhibition of α-Amylase and α-Glucosidase by Bioflavonoids

Effects of Perfluorinated Compounds on GnRH Gene Expression in vitro

Immunohistochemistry Studies of Tumor Necrosis Factor Αlpha and Interferon Gamma Expression in Pseudocapillaria tomentosa Infected and Uninfected Zebrafish

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