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Filtering by: Creator Simonich, Staci L. Massey Resource Type Undergraduate Thesis

Toxicity Screening of Polycyclic Aromatic Hydrocarbons (PAHs) in Primary Human Bronchial Epithelial Cells

Creator:

Amador, Samantha B.

Abstract:

Polycyclic aromatic hydrocarbons (PAHs) are a known class of chemicals that are linked to a multitude of adverse health outcomes. There are over 1,500 of these chemicals across various families and subgroups. 16 of these PAHs, known as parent PAHs, are identified by the EPA for focused risk assessment within...

Resource Type:

Undergraduate Thesis

Full Text:

, Glenn Wilson, David Schmedding, Carol Higginbotham, Jennifer Field, and Staci Massey Simonich. (2008
Utilization of structure-activity-relationship for predicting chemical toxicity in primary human lung cells

Creator:

Galbreath, Amanda

Abstract:

There is a growing need to establish alternative approaches for assessing hazard from chemical exposure compared to the traditional method of animal testing. Approaches that relate chemical structure to biological activity are gaining acceptance in the field as in silico methods for characterizing and predicting chemical toxicity. In this study,...

Resource Type:

Undergraduate Thesis

Full Text:

://doi.org/10.1016/j.dib.2019.104821. Geier, Mitra C., Anna C. Chlebowski, Lisa Truong, Staci L. Massey
Toxicity and Mutagenicity of Polycyclic Aromatic Hydrocarbons in Contaminated Soils using Mammalian In Vitro Assay

Creator:

Luker, George W.

Abstract:

There exists a growing need to establish a better in vitro model for evaluating PAH toxicity and carcinogenicity and to improve assessments of risk to human health, especially to the complex mixtures that exist in the environment. Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants due to the incomplete combustion...

Resource Type:

Undergraduate Thesis

Full Text:

classification of the soil extracts obtained from the Puget Sound Superfund site was performed by the Simonich