Index Catalog // ScholarsArchive@OSU

Study of sulfite mutants of Saccharomyces cerevisiae

Creator:: Wightman, JoLynne Dee
Abstract:: Sulfite mutants representing five complementation groups, previously derived from an ethyl methanesulfonate-treated haploid strain of Saccharomyces cerevisiae were studied. Although the wildtype S. cerevisiae strain used (isogenic to X2180-1 A) had a basal tolerance for sulfite (7 μM free H₂SO₃), the sensitive and resistant mutants were found to tolerate less...
Resource Type:: Masters Thesis
Full Text:: rate of damaging effect depends on sulfite concentration, pH, temperature, physiological state of

Product formulation of phenylbutazone, theophylline, tolbutamide and pharmacokinetics-toxicities of theophylline injections in pigs

Creator:: Suvanakoot, Uthai
Abstract:: A two-part study was conducted with three poorly water soluble drugs (phenylbutazone, tolbutamide, theophylline) to develop two new drug delivery systems based on physical-chemical approaches. In the first part, tolbutamide and phenylbutazone were made into solid dispersions with various excipients using a lyophilization technique. In vitro dissolution studies of these...
Resource Type:: Dissertation
Full Text:: physiological availability from solid dosage forms are largely dependent upon having the drug in the dissolved

Morphine-codeine interactions in rodents

Creator:: Blank, Jerome W.
Abstract:: Rats given morphine-codeine combinations exhibited significantly increased hotplate reaction times compared with rats given an analgesic dose of one agent alone. Genera, species, sex, protein binding and metabolism were studied as possible implicating factors for the increased reaction times. Both male and female rats exhibited increased reaction time, and showed...
Resource Type:: Masters Thesis
Full Text:: onset and duration of the effect. When both analgesic and nonanalgesic doses of one agent were given

Work load and S-T segment changes during monitored bicycle ergometer exertion following varied carbohydrate feedings and vitamin B-6 supplementation

Creator:: Siemann, Art W.
Abstract:: The purpose of this study was to monitor coronary responses occurring in the S-T segment of an electrocardiogram before, during and after exercise following a "standard" carbohydrate-loading schedule with varied vitamin B-6 supplementation. The study was conducted using four college-aged males who had been training a minimum of two years...
Resource Type:: Masters Thesis
Full Text:: control sessions and the experimental sessions would indicate the effect the experimental diet would

Hemoglobin adducts of the organophosphate insecticide azinphos-methyl

Creator:: Bailey, Bonnie J.
Abstract:: Reported here is an investigation to determine if azinphos-methyl (AZM), an organophosphate insecticide, adducts to hemoglobin, and if so, whether the hemoglobin adduct could be used as a quantitative marker of occupational AZM exposure. We hypothesized that AZM, or a metabolite of AZM, binds to hemoglobin in erythrocytes forming an...
Resource Type:: Dissertation
Full Text:: physiological role for that enzyme has been defined, use of the term cholinesterase assumes AChE unless

Indole-3-carbinol and 3,3'-diindolylmethane : relative potency as modulators of drug metabolism and carcinogenesis

Creator:: Katchamart, Sirinmas
Abstract:: Indole-3-carbinol (I3C), the most abundant metabolite of glucobrassicins, is found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage and cauliflower. I3C has been shown to have anticarcinogenic activity against many chemical carcinogens in multiple target organs in animal models. However, the anticarcinogenic activity of I3C is considered indirect since...
Resource Type:: Dissertation
Full Text:: supplementation are its estrogenic effect as seen in trout and its ability to induce cytochrome P45 Os involved

Dissimilation of nonnitrogenous compounds by Acetobacter pasteurianum

Creator:: Kawasaki, Elwell Hachiro
Resource Type:: Masters Thesis
Full Text:: inhibited the oxygen consumption even in the absence of arsenite. The arsenite effect on the carbon

Terminal oxidation pathways in Acetobacter suboxydans

Creator:: Kitos, Paul Alan
Resource Type:: Dissertation
Full Text:: . . . . . . . . . . . . . , . 64 1. pH Effect on aueose Oxidation . . . 6 2. Nuoleotide 3pecificity of G-o-P Dehydrogenase and

The physiological activity of some plant estrogens

Creator:: White, Ronald J.
Resource Type:: Masters Thesis
Full Text:: The physiological activity of some plant estrogens T9E

Some effects of plant estrogens on animals

Creator:: Noteboom, William Duane
Resource Type:: Masters Thesis
Full Text:: roproduotton by teedthg çen1atein to prerant females. The effect of genlateln did not carry over to the young

Certain physiological and pharmacological effects of radiation on rabbits

Creator:: Wagelie, Edwin Gan
Abstract:: Data were taken, following irradiation exposure to 100r and 300r cumulative dose, on 89 rabbits of three breeds that vary greatly in body size. Hematological, intestinal motility, and ear vascularity examinations were performed. Least square estimates have been obtained and an analysis of variance has been conducted in order estimate...
Resource Type:: Dissertation
Full Text:: Certain Physiological and Pharmacological Effects of

Use of radiation resistant organism as a protectant from lethal effects of irradiation in mice

Creator:: Kilbourn, Joan Priscilla Payne
Resource Type:: Dissertation
Full Text:: irradiation protected some of them from a lethal dose of irradiation. The effect of extracts from the

Glycogen utilization in newborn rats subjected to cold stress

Creator:: Van Tassel, Loren Eugene
Abstract:: Newborn rats exhibit a torporous response to cold stress at 2°C from which they revive after several hours exposure even though respiratory, cardiovascular, and muscular movements have ceased. At less severe temperatures (20 to 25°C) the rats respond with a non-torporous decrease in metabolic and physiologic activity and a lowering...
Resource Type:: Masters Thesis
Full Text:: temperature and time 3 Survival of newborn rats following exposure to temperature of 2" - 5" C 4 Effect of

A metabolic function of selenium, assessed with rat liver homogenates

Creator:: Bull, Richard Charles
Abstract:: In three separate trials rats were fed either a basal diet deficient in selenium and vitamin E or the same diet supplemented with one or both of these factors. In addition to these treatments in two of the trials, ethoxyquin was included to provide adequate lipid antioxidant protection and to...
Resource Type:: Dissertation
Full Text:: beneficial effect upon reproduction in the rat. Somewhat later Poley et al. (1941), also conducting a

In vivo and in vitro metabolism of 4-benzo(b)thienyl-N-methylcarbamate and 4-hydroxy benzothiophene by the white rat

Creator:: Miaullis, John Bartley
Abstract:: In vitro studies of Mobam (4-benzo(b)thienyl N-methylcarbamate) metabolism have demonstrated that at least three ether soluble metabolites are formed in a microsomal system fortified with reduced triphosphopyridine nucleotide (NADPH). One of the metabolites was identical to 4HBT (4-hydroxy benzothiophene), the phenol of Mobam. The other two metabolites did not possess...
Resource Type:: Masters Thesis
Full Text:: dependent on their stability in the physiological environment. In addition to ester cleavage, other

Effects of radiation on selection progress in mice

Creator:: Womack, James Ernest
Abstract:: The effects of x-irradiation on quantitative genetic traits was investigated by comparing the response of irradiated mice to selection for litter size and 28-day weight with the response to selection for the same two traits in non-irradiated lines. Irradiated lines were maintained at three levels of x-irradiation, 25 r, 50...
Resource Type:: Dissertation
Full Text:: interaction of genetic and physiological factors was assumed to be responsible for the reduced fertility

In vivo and in vitro metabolism of 4-benzo(b)thienyl-N-methylcarbamate and 4-hydroxy benzothiophene by the white rat

Creator:: Miaullis, John Bartley
Abstract:: In vitro studies of Mobam (4-benzo(b)thienyl N-methylcarbamate) metabolism have demonstrated that at least three ether soluble metabolites are formed in a microsomal system fortified with reduced triphosphopyridine nucleotide (NADPH). One of the metabolites was identical to 4HBT (4-hydroxy benzothiophene), the phenol of Mobam. The other two metabolites did not possess...
Resource Type:: Masters Thesis
Full Text:: dependent on their stability in the physiological environment. In addition to ester cleavage, other

Manganese absorption by barley roots

Creator:: Maas, E. V. (Eugene Vernon), 1936-
Abstract:: An investigation of Mn uptake by five-day-old excised barley roots revealed that a metabolically-mediated process was involved. In short-term experiments, the rate of Mn absorption was comparable to that of the macronutrient cations. Like other metabolically absorbed cations, the Mn absorption rate was a direct function of the ambient concentration...
Resource Type:: Dissertation
Full Text:: studied, Li alone had a pronounced stimulatory effect while Na, K and Rb markedly reduced the absorption

Effects of radiation on selection progress in mice

Creator:: Womack, James Ernest
Abstract:: The effects of x-irradiation on quantitative genetic traits was investigated by comparing the response of irradiated mice to selection for litter size and 28-day weight with the response to selection for the same two traits in non-irradiated lines. Irradiated lines were maintained at three levels of x-irradiation, 25 r, 50...
Resource Type:: Dissertation
Full Text:: interaction of genetic and physiological factors was assumed to be responsible for the reduced fertility

Radiation inhibition of salt-water adaptation in fish

Creator:: Monie, Herbert Joseph
Abstract:: Four species of euryhaline teleosts (chinook salmon, Oncorhynchus tshawytscha, Walbaum; staghorn sculpin, Leptocottus armatus, Girard; starry flounder, Platichthys stellatus, Pallas; shiner perch Cymatogaster aggregata, Gibbons) were exposed to x-rays. The irradiated animals were maintained in either of two different environments. The effects of x-radiation were determined by observing the percent...
Resource Type:: Masters Thesis
Full Text:: . Analytical Techniques 13 III. RESULTS 15 A. Mortalities 15 B. Physiological Changes 15 C

Naphthalene resistance in a house fly strain : its inheritance and characteristics

Creator:: Schafer, James Arnold
Abstract:: A combination of genetical and biochemical methods were utilized in investigating house fly resistance to naphthalene. The inheritance of resistance was determined by crossing a naphthalene resistant strain of Musca domestica L. with a susceptible mutant marker strain. Biochemical comparisons were made on substrains isolated from the progeny of these...
Resource Type:: Masters Thesis
Full Text:: effect suggests that slow absorption (chromosome III) and active detoxication of naphthalene

Influence of dietary selenium on the distribution of tritium-labeled vitamin E in the rate

Creator:: Cheeke, Peter R.
Abstract:: A series of four trials were conducted to determine the influence of selenium supplementation of a selenium- and vitamin E-deficient basal diet on the absorption, excretion, tissue distribution and placental transfer of a single dose of tritium-labeled α-tocopherol in the rat. In the first trial, the effect of supplementation of...
Resource Type:: Dissertation
Full Text:: the rat. In the first trial, the effect of supplementation of the basal diet with 1. 0 ppm selenium

The effect of dimethyl sulfoxide (DMSO) on the radiosensitivity of the rough-skinned newt (Taricha granulosa)

Creator:: Lappenbusch, William L.
Abstract:: More than 2,000 male newts were collected during the summer and maintained unfed at 10°C both pre- and post-irradiation. Exposures ranging up to 30 kR were given with 300 kVp X-rays and ⁶⁰Co gamma rays. Half of the newts were injected (I. P.) with 15 g DMSO/kg (the maximum sublethal...
Resource Type:: Dissertation
Full Text:: The effect of dimethyl sulfoxide (DMSO) on the

Histologic effects of chronic selenium deficiency in selected tissues of laboratory rats

Creator:: Sprinker, Lucas Harry
Abstract:: The selenium-responsive syndromes and the discovery of Factor 3-selenium focused attention on selenium in metabolism. Two hypotheses have been advanced to explain the metabolic effect of selenium: 1) substitution or sparing of alpha tocopherol, and 2) a primary role in metabolism. The first hypothesis is supported by Scott and Desai,...
Resource Type:: Masters Thesis
Full Text:: metabolic effect of selenium: 1) substitution or sparing of alpha tocopherol, and 2) a primary role in

The effect of selenium on chemical carcinogenicity in the rat

Creator:: Johnston, Weldon Kearney
Abstract:: One hundred and fifty-one weanling rats of both sexes were fed control diets or diets containing 160 ppm diethylnitrosamine (DEN) or 150 ppm N-2-fluorenyl-acetamide (FAA). The carcinogen level was calculated so that the LD₅₀ should be achieved at about 17 weeks. Each carcinogen treatment was incorporated with three different diet...
Resource Type:: Masters Thesis
Full Text:: The Effect of Selenium on Chemical Carcinogenicity in the

Effects of x-irradiation on DNA synthesis in salivary gland cells of Drosophila hydei

Creator:: Wong, Patrick Tin-Choi, 1942-
Abstract:: The effect of X-irradiation on DNA synthesis in larval salivary glands of Drosophila hydei was studied using the technique of liquid scintillation spectrometry and autoradiography. DNA synthesis in salivary glands of synchronized larvae was measured at successive stages of third instar development by in vitro uptake of ³H-thymidine for a...
Resource Type:: Dissertation
Full Text:: Paul A. Roberts The effect of X-irradiation on DNA synthesis in larval salivary glands of Drosophila

Temperature and the bioenergetics of Cichlasoma bimaculatum

Creator:: Sethi, Hari Singh
Abstract:: One means of evaluating the temperature requirements of an animal is to determine changes temperature causes in the uses and losses of energy and materials in the food the animal consumes. To develop energy budgets for cichlids (Cichlasoma bimaculatum) at different temperatures (20, 24, 28, 32 and 36 C) data...
Resource Type:: Dissertation
Full Text:: determines the limits within which the animal is free to perform. Some of the pertinent physiological

The uptake, retention, and distribution of ⁶⁰Co, ⁶⁵Zn, ⁸⁵Sr, and ¹³¹I in the rough-skinned newt (Taricha Granulosa) : A radio-ecological study

Creator:: Valett, Bryan Batson
Abstract:: The uptake, retention, and distribution of ⁶⁰Co, ⁶⁵Zn, ⁸⁵ Sr, and ¹³¹I was examined in the Rough-Skinned Newt (Taricha granulosa). Each of these radionuclides is a possible contaminant of the freshwater environment and, thus, is of importance in radioecology. The newts were maintained singly at 10° C in an unfed...
Resource Type:: Dissertation
Full Text:: form complexes with organic materials. Thus, cobalt is potentially useful in physiological processes

Pulmonary function of male cigarette smokers compared with lifetime noncigarette smokers

Creator:: Barr, Robert Douglas
Abstract:: The pulmonary function scores of 250 male cigarette smokers were compared with 406 lifetime nonsmokers. A Stead-Wells spirometer was used to obtain forced vital capacity, forced expiratory flow, forced mid-expiratory flow, and forced expiratory volume. All individuals included in the sample were between. the ages of 20 and 49 years....
Resource Type:: Dissertation
Full Text:: American Physiological Society for lung volumes and for various phases of pulmonary research. Pulmonary

The visual response of the purple shore crab, Hemigrapsus nudus, to ionizing and non-ionizing radiation

Creator:: Jordan, Neil Michael
Abstract:: Bioelectric responses from the isolated eye of the purple shore crab were measured by the electroretinogram with stimulation by light from wavelengths of 250 to 800 nm, strontium-yttrium-90 beta radiation, 17.5 keV x-radiation, and 3-cm microwaves. Peak sensitivities to light stimulation were found at 350 and 500 nm. These peaks...
Resource Type:: Masters Thesis
Full Text:: even when the eye was excised. A temperature effect was also noted by this author, in which an

Histogenesis of fetal rat lung and liver after x-irradiation in organ culture and in utero

Creator:: Vogt, Judith C.
Resource Type:: Dissertation
Full Text:: Radiation Studies on Lung Cultures 36 Properties of Connective Tissue 38 Properties of Collagen 41 Effect of

Effects of dieldrin on the intrinsic rate of increase of the guppy, Poecilia reticulata Peters

Creator:: Roelofs, Terry Dean
Resource Type:: Dissertation
Full Text:: increase becomes more of a physiological parameter, the value of which is de- pendent upon existing

The influence of calcium carbonate and clacium gluconate on tetracycline absorption in man

Creator:: Owings, Gary Lee
Abstract:: This experiment was designed to investigate the in vivo effects of calcium ions on tetracycline absorption when oral doses of tetracycline and calcium-containing medications were administered concurrently. Twenty-one human volunteers were selected and divided into three equal-sized groups: Group A, Group B, and Group C. Each volunteer in Group A...
Resource Type:: Masters Thesis
Full Text:: depressant effect of calcium carbonate on tetracy- cline absorption was significantly greater than the

Absorption of benzocaine -³H from semi-solid dosage forms following rectal administration in rats

Creator:: Lorskulsint, Duangchit
Abstract:: The effect of concentration, vehicle and surfactant on the absorption of benzocaine -³H across the rat's rectal mucosa was investigated. Blood radioactivity levels were determined after the application of benzociane -³H containing suppositories and ointments. A wet oxidation method was used for sample digestion. Since the radioactivity counted is the...
Resource Type:: Masters Thesis
Full Text:: Agents Effect on Absorption 14 Effect of Physiological Changes on Absorption 17 Absorption of Topical

Calcium regulation and physiological function in animals exposed to lead

Creator:: Hoffman, Norbert Edward
Abstract:: Tissue distribution studies of calcium and lead in brain tissue of rats were increased subsequent to a single intravenous injection of lead, 10 mg/kg, in the form of lead acetate. Time-course studies demonstrated that brain concentrations of calcium and lead (in terms of wet tissue weight) were found to be...
Resource Type:: Dissertation
Full Text:: Calcium regulation and physiological function in animals

Effect of cadmium on ceruloplasmin levels in the rat

Creator:: Robinson, Alfred Vern
Abstract:: Injection of a 2.0 mg Cd ²⁺ /kg B.W. (I.P. as CdC1 ₂ in .05 M NaAc, pH = 6.9-7.2, .15 M or p = .15 with NaCl) resulted in a decrease in ceruloplasmin (EC 1.12.3) p-phenylenediamine oxidase activity within one hour of injection. Maximal decrease (40%) occurred within six...
Resource Type:: Masters Thesis
Full Text:: Science presented on natMi /4 /92,2 (Major Department) (Date) Title: EFFECT OF CADMIUM ON CERULOPLASMIN

A comparison of a smoking and nonsmoking population using the forced expiratory flow in the seventy-five to eighty-five percent segment of the spirometric curve

Creator:: Breese, John David
Abstract:: Forced vital capacity lung expiration examinations of nonsmoking and cigarette-smoking male sample populations were compared to determine if the 75 to 85 percent segment was a more sensitive test of early lung dysfunction. The nonsmoking population was composed of 240 men who were tested for values of forced vital capacity...
Resource Type:: Masters Thesis
Full Text:: and pulmonary dimensions. II FEF75_85% analysis of variance testing effect of smoking, age and height

The effect of selenium deficiency on the fatty acid metabolism of rats and lambs

Creator:: Fischer, William Carl
Abstract:: Selenium deficiency in rats results in increased carbon metabolism, approaching twice the rate of selenium supplemented animals (normal). This is also reflected in a 50 percent increase in lysosomal enzyme activity in tissues of selenium deficient animals. Isolation of rat liver lysosomes shows a 17 percent increase in membrane thickness...
Resource Type:: Dissertation
Full Text:: , 1974 (Major Department) Title: THE EFFECT OF SELENIUM DEFICIENCY ON THE FATTY ACID METABOLISM OF RATS

Behavioral and electrophysiological evidence for the mechanisms involved in the detection of ionizing radiations by the crayfish Pacifastacus trowbridgii

Creator:: Rodriguez, Adrian
Abstract:: The light-adapted crayfish, Pacifastacus trowbridgii (Stimpson, 1957), displayed a behavioral response to exposure to 300 kV x-rays at exposure rates of 10 to 30 R/s. Within this range, the proportion of subjects that responded increased with an increase in exposure rate. The response latency was inversely proportional to the exposure...
Resource Type:: Dissertation
Full Text:: - physiological tests. The presence of chemoreceptors was indicated by responses elicited after administration of

Selenium effects and species differences in hepatic metabolism of pyrrolizidine alkaloids and other xenobiotics

Creator:: Shull, Lee R.
Abstract:: The metabolism of pyrrolizidine alkaloids and other drugs was studied with regard to nutritional status and species differences. Pyrrolizidine alkaloids which are biotransformed to severely toxic metabolites were isolated from tansy ragwort (Senecio jacobaea). Semi-purified alkaloid crystals containing five alkaloids (senecionine, seneciophylline, jacobine, jacoline, and jacozine) were prepared and found...
Resource Type:: Dissertation
Full Text:: liver weight, but had no effect on microsomal oxidases. Similarly, high copper had no effect on the

Some aspects of the mechanism of estrogen action in the uterus of the ewe

Creator:: Koligian, Karl Bruce
Abstract:: The binding of estrogen to endometrium and uterine arteries of the ewe was investigated by use of a [³H]estradiol exchange assay and by incubating whole tissue aliquants with [³ H]estradiol, a method which permits quantification of bound estrogen translocated from the cytoplasm to the nucleus. Five ewes were necropsied on...
Resource Type:: Dissertation
Full Text:: arteries on day 10 only. The effect of estrogen and progesterone on concentra- tions of estrogen

The uptake and retention of cesium-134 in Microtus canicaudus Miller

Creator:: Lei, Wayne
Abstract:: A study was performed to assess the uptake and retention patterns of cesium-134 in the gray-tailed vole, Microtus canicaudus Miller. To furnish a realistic source of contaminated food for the voles, wheat seedlings were raised in hydroponic solutions to provide radiocesium labeled wheat clippings. The hydroponic system was designed to...
Resource Type:: Masters Thesis
Full Text:: relatively high energies of emitted radiation (Davis, 1963). In addition, cesium is a physiological analog

Some possible roles for selenium in the reproductive physiology of the male graytailed vole (Microtus canicaudus)

Creator:: Whitfield, Stephen Curtiss
Abstract:: The testes of the gray-tailed vole (Microtus canicaudus Miller) exhibited a high affinity for selenium relative to other selected tissues. Uptake of selenium-75 in the testis-epididymis complex was delayed relative to uptake by the whole body, kidney, and liver. This pattern of uptake suggested that selenium was metabolically incorporated into...
Resource Type:: Masters Thesis
Full Text:: E in the diet, the addition of selenium produced no significant changes in measured physiological

Effects of fractionated radiation doses on survival times of the newt (Taricha granulosa)

Creator:: Campbell, Carol Lee
Abstract:: This was a study designed to determine the occurrence of recovery from radiation damage in Taricha granulosa. Irradiation with either gamma or x-ray sources in the range of 96-10,000 rads was given. (The mean or median survival times were determined.) Doses were fractionated and the survival times for the same...
Resource Type:: Masters Thesis
Full Text:: greatest importance. If the fractionation interval was too short, a merely additive effect of the

Exposure to ultraviolet-B radiation : sensitivity evaluation of an important ecological parameter of the marine copepod Acartia clausi

Creator:: Karanas, James J.
Abstract:: The ozone present in the atmosphere filters incident solar ultraviolet (UV) radiation such that only the longer wavelengths of the total UV spectrum emitted by the sun reach the earth's surface. Atmospheric increases in nitrogen oxides and chlorofluoromethanes represent a threat to the existence of this protective screen. As the...
Resource Type:: Masters Thesis
Full Text:: hatching of A. clausi eggs. 31 11 The effect of temperature on development time of A. clausi eggs for two

Diurnal variations of body temperature and reaction time accompanying early morning and evening aerobic routines

Creator:: Smith, Ella Jean
Abstract:: The primary purpose of this study was to determine the effects of early morning and evening bouts of aerobic exercise upon the diurnal pattern of reaction time and body temperature. An effort was made to classify subjects according to the rhythmic trends identified with 'morning' and 'evening' type persons. Eight...
Resource Type:: Masters Thesis
Full Text:: to detect physiological and psychological orientation to the two extremes of day. Treatments

Selenium-75 incorporation in semen and reproductive organs of the bull and ram

Creator:: Pond, Finn Richard
Resource Type:: Dissertation

The lethal response of the roughskin newt, Taricha granulosa (Skilton), to ultraviolet-B radiation at three fluence rates

Creator:: Michaelis, Barbara
Abstract:: Roughskin newts, Taricha granulosa (Skilton), were exposed to UV-B (280-320nm), UV-A (321-380 nm), and visible radiation from fluorescent sunlamps (Westinghouse FS40) that were filtered with cellulose acetate film. UV-B controls were exposed to irradiation from sunlamps that were filtered with Mylar-D, a polyester film that effectively absorbed UV-B radiation while...
Resource Type:: Masters Thesis
Full Text:: the fluence rate threshold for Taricha. A dose rate effect appears to exist, with respect to LD50

Pharmacokinetics of theophylline and it's N-7 derivatives in rabbits

Creator:: Tavipatana, Wattanaporn
Abstract:: Pharmacokinetics of theophylline and N-7 substituted theophylline in rabbits when administered alone and in various combinations were investigated. This thesis has four chapters dealing with etophylline and theophylline; proxyphylline and theophylline; dyphylline and theophylline; and etophylline, proxyphylline and dyphylline pharmacokinetics when administered concomitantly. All chapters are interrelated. Each chapter has...
Resource Type:: Masters Thesis
Full Text:: has no significant effect on the pharmacokinetic behavior of theophylline, including protein or

The effectiveness of the Po₂ Aerobic Exerciser in simulating high altitude training at sea level in cross country runners

Creator:: Sievers, Gary K.
Abstract:: Purpose: The purpose of this study was to determine the effectiveness, if any, of the P0₂ Aerobic Exerciser in simulating high altitude training in cross country runners living at sea level. Procedures: This study was conducted during the 1982 winter term at Oregon State University. Four cross country runners of...
Resource Type:: Masters Thesis
Full Text:: design. Physiological tests were: the Balke submaximal treadmill test to measure changes in Vol max

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