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Pharmacokinetic investigation of a potential drug interaction : aminophylline and prednisone

Creator:

Anderson, John L.

Resource Type:

Masters Thesis

Full Text:

Potential Drug Interaction: Aminophylline and Prednisone Abstract approved: Redacted for Privacy es W
The asymmetric binding of Actinomycin D to DNA hexamers

Creator:

Ivancic, Monika

Abstract:

The solution structure determination of DNA molecules has been an important part of structural biology. NMR solution structures are a complement to structures solved via X-ray crystallography; the two methods are the only ways of obtaining three dimensional coordinates of macromolecules. Because of the nature of the molecule, the solution...

Resource Type:

Dissertation

Full Text:

examined using NMR spectroscopy, including drug-bound DNA complexes. Most previous studies of complexes
Modification of the acute effects of ethanol or acetaldehyde on drug metabolism by ascorbic acid, thiamine, or cysteine in vivo

Creator:

LaFollette, Sharron E.

Abstract:

The inhibition of mixed-function oxidase (MFO) activity by ethanol or acetaldehyde was examined in vivo by monitoring changes in salivary half-life of antipyrine or aminopyrine in adult male Sprague-Dawley rats. Ethanol (1-6 g/kg, po) or acetaldehyde (4-8 mmol/kg, ip) was administered 20 minutes prior to antipyrine (100 mg/kg, ip) or...

Resource Type:

Dissertation

Full Text:

acetaldehyde on drug metabolism by ascorbic acid, thiamine, or cysteine in vivo AN ABSTRACT OF THE THESIS OF