Baculoviruses comprise a diverse group of pathogens
infectious for members of the insect orders Lepidoptera, Hymenoptera
and Diptera. Of the three subgroups, two (subgroup A, nuclear
polyhedrosis virus (NPV) and subgroup B, granulosis virus (GV) are
occluded in a crystalline protein structure while the remaining
subgroup (subgroup C, non-occluded virus)...
In this study, the gene expression levels between 6 month old mice and 26 month
old mice were compared. The purpose of this research was to identify genes that are
differentially regulated due to aging. The results showed 148 significantly differentiated
genes in the analysis of a total of 44,170...
Full Text:
F.
Gombart,
Ph.D.
HHMI
Summer
2012
Oregon
State
University
In this study, the gene expression levels between 6 month old mice and 26 month
old mice were compared. The purpose of this research was to identify genes that are
differentially regulated due to aging. The results showed 148 significantly differentiated
genes in the analysis of a total of 44,170...
Full Text:
Gene Expression Related to the Decline of the Aging Immune System
Jenny Tran and AdrianF. Gombart
Background: Antimicrobial peptides (AMPs) are synthesized and secreted by immune and epithelial cells that are constantly exposed to environmental microbes. AMPs are essential for barrier defense and deficiencies lead to increased susceptibility to infection. In addition to their ability to disrupt the integrity of bacterial, viral and fungal membranes, AMPs...
Full Text:
, AdrianF. Gombart
1,2
1
Linus Pauling Institute,
2
Department of Biochemistry and Biophysics, Oregon
Background: Antimicrobial peptides (AMPs) are synthesized and secreted by immune and epithelial cells that are constantly exposed to environmental microbes. AMPs are essential for barrier defense and deficiencies lead to increased susceptibility to infection. In addition to their ability to disrupt the integrity of bacterial, viral and fungal membranes, AMPs...
Background: Antimicrobial peptides (AMPs) are synthesized and secreted by immune and epithelial cells that are constantly exposed to environmental microbes. AMPs are essential for barrier defense and deficiencies lead to increased susceptibility to infection. In addition to their ability to disrupt the integrity of bacterial, viral and fungal membranes, AMPs...
Using microRNA array analyses of in vitro HIV-1-infected CD4(+) cells, we find that several host microRNAs are significantly up- or downregulated around the time HIV-1 infection peaks in vitro. While microRNA-223 levels were significantly enriched in HIV-1-infected CD4(superscript+)CD8(superscript-) PBMCs, microRNA-29a/b, microRNA-155 and microRNA-21 levels were significantly reduced. Based on the...
The light-adapted crayfish, Pacifastacus trowbridgii (Stimpson,
1957), displayed a behavioral response to exposure to 300 kV x-rays at
exposure rates of 10 to 30 R/s. Within this range, the proportion
of subjects that responded increased with an increase in exposure
rate. The response latency was inversely proportional to the
exposure...