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Filtering by: Creator Goyer, A. Rights Statement Copyright Not Evaluated

A cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism

Creator:

Goyer, Aymeric, Hasnain, Ghulam, Frelin, Oceane, Ralat, Maria A., Gregory, Jesse F., III, and Hanson, Andrew D.

Abstract:

Genes specifying the thiamin monophosphate phosphatase and adenylated thiazole diphosphatase steps in fungal and plant thiamin biosynthesis remain unknown, as do genes for thiamin diphosphate (ThDP) hydrolysis in thiamin metabolism. A distinctive Nudix domain fused to thiamin diphosphokinase (Tnr3) in Schizosaccharomyces pombe was evaluated as a candidate for these functions....

Resource Type:

Article

Full Text:

Goyer*1,2, Ghulam Hasnain†1, Océane Frelin†, Maria A. Ralat‡, Jesse F. Gregory III‡ and Andrew D