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Nanostructured Lipid Carriers as Multifunctional Nanomedicine Platform for Pulmonary Co-Delivery of Anticancer Drugs and siRNA

Creator:

Taratula, Oleh, Kuzmov, Andriy, Shah, Milin, Garbuzenko, Olga B., and Minko, Tamara

Abstract:

We developed, synthesized, and tested a multifunctional nanostructured lipid nanocarrier- based system (NLCS) for efficient delivery of an anticancer drug and siRNA directly into the lungs by inhalation. The system contains: (1) nanostructured lipid carriers (NLC); (2) anticancer drug (doxorubicin or paclitaxel); (3) siRNA targeted to MRP1 mRNA as a...

Resource Type:

Article

Full Text:

, Andriy Kuzmov, Milin Shah, Olga B. Garbuzenko, Tamara Minko PII: S0168-3659(13)00237-X DOI: doi: 10.1016
Remediation of heavy-metal contaminated soils using succinic acid

Creator:

Kaul, Arvind

Abstract:

Succinic acid, a low molecular weight dicarboxylic acid was used to leach out heavy metals from Willamette Valley soil (contaminated separately with lead, copper, and zinc) in form of water-soluble organo-metal complexes. The research tasks included developing synthetic contaminated soils representative of those found at Superfund sites and making heavy...

Resource Type:

Masters Thesis

Full Text:

activity of Its constituent ions in solution. At equilibrium 1Mni 1.+ m1-MILIn (s) (aq) (aq) Ksp as