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Mechanistic studies of the racemization of optically active phenyl benzenethiolsulfinate and related reactions

Creator:

Large, George Blackmore

Resource Type:

Dissertation

Full Text:

(RS -O -SR) and as thiolsulfinates, esters of the hypothetical thiol- sulfinic acid. Zincke and
Mitochondrial glutathione and the effect of perturbed calcium homeostasis on rat hepatocyte thiols

Creator:

Olafsdottir, Kristin

Abstract:

Recent studies have demonstrated that perturbations of intracellular thiol and calcium homeostasis may be important events in the early development of cell injury by toxic chemicals. Incubation of isolated rat hepatocytes in a calcium free medium, severely depleted intracellular Ca²⁺ levels and resulted in the loss of both cytosolic and...

Resource Type:

Dissertation

Full Text:

intracellular thiol and calcium homeostasis may be important events in the early development of cell injury by