Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Verchot, Jeanmarie Rights Statement Copyright Not Evaluated

Evidence that the Potyvirus P1 Proteinase Functions in trans as an Accessory Factor for Genome Amplification

Creator:

Verchot, Jeanmarie and Carrington, James C.

Abstract:

The tobacco etch potyvirus (TEV) polyprotein is proteolytically processed by three viral proteinases (NIa, HC-Pro, and P1). While the NIa and HC-Pro proteinases each provide multiple functions essential for viral infectivity, the role of the P1 proteinase beyond its autoproteolytic activity is understood poorly. To determine if P1 is necessary...

Resource Type:

Article

Full Text:

Functions in trans as an Accessory Factor for Genome Amplification JEANMARIE VERCHOT AND JAMES C
Debilitation of Plant Potyvirus Infectivity by P1 Proteinase-Inactivating Mutations and Restoration by Second-Site Modifications

Creator:

Verchot, Jeanmarie and Carrington, James C.

Abstract:

Tobacco etch virus (TEV) encodes three proteinases that catalyze processing of the genome-encoded polyprotein. The P1 proteinase originates from the N terminus of the polyprotein and catalyzes proteolysis between itself and the helper component proteinase (HC-Pro). Mutations resulting in substitution of a single amino acid, small insertions, or deletions were...

Resource Type:

Article

Full Text:

Infectivity by P1 Proteinase-Inactivating Mutations and Restoration by Second-Site Modifications JEANMARIE