Index Catalog // ScholarsArchive@OSU

Identifying the Enzymes Responsible for Reduction of Doxorubicin to its Cardiotoxic Metabolite Doxorubicinol using a Novel Immunoclearing Approach

Creator:: Breysse, Daniel H.
Abstract:: Doxorubicin is a widely used cancer therapeutic, but its effectiveness is limited by cardiotoxic side effects. Evidence suggests cardiotoxicity is due not to doxorubicin, but rather its metabolite, doxorubicinol. Identification of the enzymes responsible for doxorubicinol formation is important in developing strategies to prevent cardiotoxicity. In this study, the contributions...
Resource Type:: Masters Thesis
Full Text:: AN ABSTRACT OF THE THESIS OF Daniel Breysse for

Factors affecting within-season and between-season breeding dispersal of burrowing owls in California

Creator:: Catlin, Daniel H.
Abstract:: Dispersal is integral to our understanding of the life history and population biology of many vertebrates, but difficulties in detecting long distance movements have complicated its study. Moreover, studies of factors affecting dispersal are often unable to determine the relative contributions of variables such as nesting success, mate fidelity, and...
Resource Type:: Masters Thesis

Investigating the basis of substrate specificity in butane monooxygenase and chlorinated ethene toxicity in Pseudomonas butanovora

Creator:: Halsey, Kimberly H.
Abstract:: Pseudomonas butanovora, Mycobacterium vaccae, and Nocardioides sp. CF8 utilize distinctly different butane monooxygenases (BMOs) to initiate degradation of recalcitrant chlorinated ethenes (CEs) that pollute aquifers and soils. BMO-dependent degradation of CEs such as trichloroethylene (TCE) can lead to cellular toxicities. The type and severity of TCE transformation-dependent damage can have...
Resource Type:: Dissertation
Full Text:: DISSERTATION OF Kimberly H. Halsey for the degree of Doctor of Philosophy in Molecular and Cellular

Numerical assessment of steel plate shear wall with coupling (SPSW-WC) system design procedure

Creator:: Li, Wennan
Abstract:: The Steel Plate Shear Wall (SPSW) system, is an innovative seismic lateral force resistant system, which has experienced increased use over the last three decades. The SPSW system is composed of boundary elements which anchor web plates that develop diagonal tension fields. A number of SPSW buildings have been built...
Resource Type:: Masters Thesis
Full Text:: Steel Plate Shear Wall with Coupling (SPSW-WC) System Design Procedure Abstract approved: Daniel

Upgrading of a model compound of bio-oil using carbon monoxide in high temperature water

Creator:: Phipps, Ezra Daniel
Abstract:: Meeting the energy demands of the future is one of the most important challenges facing the engineering community today. An example of this problem is transportation fuels. Most of the current transportation fuels are composed of petroleum hydrocarbons. Finding a viable alternative is important given the potential scarcity of these...
Resource Type:: Masters Thesis
Full Text:: Ezra Daniel Phipps for the degree of Master of Science in Chemical Engineering presented on May 29

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

Creator:: Alzhanov, Damir T.
Abstract:: The majority of our modern understanding of bacterial pathogenesis is based on the strategy that involves screening bacterial genomes for the presence of the genes encoding pathogenic factors, and analysis of these genes via forward and reverse genetics. Chlamydiae represent a unique group of pathogenic bacteria in which it is...
Resource Type:: Dissertation
Full Text:: Daniel D. Rockey The majority of our modern understanding of bacterial pathogenesis is

The impact of child-centered play therapy on anxiety levels in pre-neurosurgical pediatric patients

Creator:: Lerwick, Julie L.
Abstract:: The prevalence of childhood illness requiring hospitalization establishes the need for implementation of an applied intervention to decrease levels of hospitalization-induced anxiety in pediatric patients. In addition to anxiety, levels of perceived trauma have also been linked to pre-operative pediatric patients. Child-Centered Play Therapy (CCPT) within the medical setting has...
Resource Type:: Dissertation
Full Text:: : ___________________________________________________________________ Daniel Stroud The prevalence of childhood illness requiring hospitalization establishes

Large-scale laboratory observations of wave forces on a highway bridge superstructure

Creator:: Bradner, Christopher
Abstract:: The experimental setup and data are presented for a laboratory experiment conducted to examine realistic wave forcing on a highway bridge superstructure. The experiments measure wave conditions along with the resulting forces, pressures, and structural response of a 1:5 scale, reinforced concrete model of a typical section of the I-10...
Resource Type:: Masters Thesis
Full Text:: Bridge Superstructure Abstract approved: Daniel T. Cox The experimental setup and data are

Using PCR techniques to assess Chlamydia trachomatis genome

Creator:: Moo-Fuentes, Jordi C.
Abstract:: Chlamydia possesses an immense importance within both human and animal medicine when looking at pathogens. Chlamydia trachomatis infections have been shown to affect both the eye and genital tracts in millions of humans and animals every year [13]. As C. trachomatis strains are highly conserved in patients, it has made...
Resource Type:: Honors College Thesis
Full Text:: : ___________________________________________________ Daniel Dean Rockey Abstract Chlamydia possesses an immense importance within both human and

A study of the photolysis of the aqueous thymine system at 214 nm, 229 nm and 254 nm

Creator:: Satcher, Robert Lee
Abstract:: The photolysis of the aqueous thymine system has been investigated at 214 nm, 229 nm and 254 nm at room temperature. Products of photolysis have been identified as hydrogen peroxide, 6-hydroxy-5- hydroperoxy thymine and tentatively 5-hydroxy-6-hydroperoxy thymine. These together with thymine loss, were determined quantitatively under a variety of conditions....
Resource Type:: Dissertation
Full Text:: product is adduct of methanol (Wang, 1959). 0 H + CH 3 OH Thymine + Methanol -11. 28 Adduct More

ScholarsArchive@OSU

Identifying the Enzymes Responsible for Reduction of Doxorubicin to its Cardiotoxic Metabolite Doxorubicinol using a Novel Immunoclearing Approach

Factors affecting within-season and between-season breeding dispersal of burrowing owls in California

Investigating the basis of substrate specificity in butane monooxygenase and chlorinated ethene toxicity in Pseudomonas butanovora

Numerical assessment of steel plate shear wall with coupling (SPSW-WC) system design procedure

Upgrading of a model compound of bio-oil using carbon monoxide in high temperature water

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

The impact of child-centered play therapy on anxiety levels in pre-neurosurgical pediatric patients

Large-scale laboratory observations of wave forces on a highway bridge superstructure

Using PCR techniques to assess Chlamydia trachomatis genome

A study of the photolysis of the aqueous thymine system at 214 nm, 229 nm and 254 nm

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