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  • The influence of economic globalization to seafood consumption demand of Chinese residents

    Creator:
    Chen, Sun
    Abstract:
    With the economic globalization, the consumption demand of Chinese residents has changed gradually. The paper analyzes consumption tendency of Chinese residents from two aspects, those are per capital consumption level and consumption characteristics. On the one side, per capita ownership of fish and fishery products of China is above the...
    Resource Type:
    Presentation and Research Paper

  • Look Ma, no beads: Analyzing traction force characteristics of migratory adenocarcinoma in heterogeneous type-1 collagen through bead-free confocal microscopy

    Creator:
    Groves, Nicholas Scott
    Abstract:
    Current methods in traction force analysis rely on a homogeneous extra-cellular matrix and embedded microbeads to track deformations. The efficacy of these methods decreases when the matrix is not homogeneous. In heterogeneous matrices, beads often aggregate in regions of higher matrix density and float in regions where matrix substrate is...
    Resource Type:
    Undergraduate Thesis
    Full Text:
    confocal microscopy Nicholas Scott Groves Advisor: Prof. Bo Sun May 30, 2016 1 Abstract Current

  • Investigating Multimodal Therapies with Nanotechnology to Engineer Advanced Chemoradiation Platforms

    Creator:
    DuRoss, Allison N.
    Abstract:
    The potential for nanomedicine to reduce toxicity and improve therapeutic response to radiation is vast. Clinically, this potential has thus far only begun to be realized with the recent success of the radioenhancing nanoparticle, NBTXR3 by Nanobiotix. Radioenhancing nanoparticles, however, represent only a small class of nanomaterials that may be...
    Resource Type:
    Dissertation
    Full Text:
    : ______________________________________________________ Conroy Sun Abstract The potential for nanomedicine to reduce toxicity and improve

  • Multi-scale Investigation of Bidirectional Feedback Mechanism Between Breast Cancer Cells and Extracellular Matrix

    Creator:
    Kim, Jihan
    Abstract:
    Cell migration is fundamental for physiological processes such as immune re-sponses, wound healing and development. It is also a critical characteristic of metastatic cancer cells. An extensive amount of studies have focused on 2D sub-strates in order to understand the mechanism of cancer metastasis. However, much less is known about...
    Resource Type:
    Dissertation
    Full Text:
    Sun Cell migration is fundamental for physiological processes such as immune re- sponses, wound

  • Mechanics Controls Collective Cancer Invasion

    Creator:
    Alobaidi, Amani A.
    Abstract:
    Cancer cell migration in three-dimensional extracellular matrix is a major cause of death for cancer patients. Although extensive studies have elucidated detailed mechanism of single cell 3D invasion and cell-ECM interaction, 3D collective cancer invasion is still poorly understood. 3D collective migration models have unveiled unexpected degrees of diversity and...
    Resource Type:
    Dissertation
    Full Text:
    Chen, Yang Jiao, and Bo sun Physical Biology, Volume 14 4 (2017 ): 045005 Collective cellular

  • Morphodynamics of 3D Migrating Cancer Cells

    Creator:
    Eddy, Christopher Z.
    Abstract:
    At the intersection of basic science research and clinical relevance, cancer metastasis and cell invasion is a multifaceted problem that has been investigated for the past several decades. Importantly, cancer cell plasticity, the ability of a single cell to change its phenotype without genetic mutations in response to environmental cues,...
    Resource Type:
    Dissertation
    Full Text:
    of 3D Migrating Cancer Cells Abstract approved: Bo Sun At the intersection of basic science

  • Mechanics of three-dimensional microenvironments of cells

    Creator:
    Jones, Christopher
    Abstract:
    The structure and mechanics of tissues affect many important cellular functions such as migration, differentiation, and growth. Mechanical interactions between cells and the extracellular matrix (ECM), as well as ECM-mediated mechanical communication between cells, plays a part in coordinating collective cellular dy- namics during critical processes such as morphogenesis, tissue...
    Resource Type:
    Dissertation
    Full Text:
    -Dimensional Microenvironments of Cells Abstract approved: Bo Sun The structure and mechanics of tissues

  • State-of-the-Art Combination Therapies and Nanomedicines for Triple Negative Breast Cancer

    Creator:
    Fabbi, Meagan C.
    Abstract:
    Triple-negative breast cancer (TNBC) is a particularly aggressive molecular subtype of malignant cells that tends to proliferate quickly and is commonly resistant to traditional chemotherapy leading to relapses in prognosis more frequently than other forms of breast cancer (BCa) [1][2][3]. Current treatment options include surgical resection of cancerous tissue and...
    Resource Type:
    Honors College Thesis
    Full Text:
    Cancer Abstract approved: _______________________________________________________ Conroy Sun

  • Multicellular monolayer’s self-organization under external stimuli

    Creator:
    Li, Guanyu
    Abstract:
    Cell signaling under external stimulation is a critical mechanism that governs many biological processes such as cell proliferation, cell migration, and cell apoptosis, etc. For multicellular organisms, the ability to synchronize heterogeneous individual cellular responses through intercellular communication is crucial to maintain normal functionality. However, even though the biological pathways...
    Resource Type:
    Dissertation
    Full Text:
    Monolayer’s Self-organization Under External Stimuli Abstract approved: Bo Sun Cell signaling under

  • Applying Deep Learning in Street View Imagery for Environmental Health Research

    Creator:
    Zhang, Yifang
    Abstract:
    Urban green space is associated with multiple physical and mental health outcomes. Several benefits of green space, such as stress reduction and attention restoration, are dependent on visual perception of green space exposures. However, traditional green space exposure measures do not capture street-level exposures. In this project, we apply deep...
    Resource Type:
    Capstone Project
    Full Text:
    : ______________________________________________________ Dr. Lizhong Chen Urban green space is associated with multiple physical and mental