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  • Microbial degradation of linear alkylbenzenesulfonates in sewage contaminated groundwater

    Creator:
    Eby, Sean D.
    Abstract:
    Surfactants, or surface active agents, are the active ingredients in detergents used for domestic cleaning applications, such as dish washing and laundering. They are effective cleaning agents by concentrating at interfacial regions, lowering the surface tension of water, and forming micelles that solubilize oils (West, 1992). Surfactants are amphiphilic, because...
    Resource Type:
    Undergraduate Thesis

  • An Overview of SPACs and the 2020-2021 SPAC Surge

    Creator:
    Moon, Laura E.
    Abstract:
    This paper provides a literature review in order to capture the state of the Special Purpose Acquisition Company (SPAC) market, incorporating the most recent research from 2020 and 2021. SPACs are an alternative way to take a company public. Rather than going through the traditional IPO process to access public...
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ Sean Yang This paper provides a literature review in order to capture the state of the Special

  • Synthesis and SERS : Reproducible Nanostar Plasmons and a Study of Optical Enhancement

    Creator:
    Ramsey, Jacob D.
    Abstract:
    Gold nanostars are a relative newcomer to the nanoparticle scene, and their unique properties make them very desirable for spectroscopic applications. These nanoparticles, with their sharp tips, create electric field enhancements that interact with light in an advantageous way. This Thesis outlines our in-depth study of gold nanostar synthesis, the...
    Resource Type:
    Honors College Thesis
    Full Text:
    a Study of Optical Enhancement by Jacob D. Ramsey A THESIS

  • Characterization of the Cellular Respiration and Mitochondrial Metabolism in C2C12 Mouse Myoblasts

    Creator:
    Sather, Bergen K.
    Abstract:
    Type-2 diabetes (T2D) has become a pandemic. The main impairment in T2D is skeletal muscle insulin resistance (IR) and is often associated with obesity. Despite decades of study, the mechanisms of IR have not been fully resolved. Evidence has implicated mitochondrial dysfunction as a potential cause and/or consequence of IR....
    Resource Type:
    Honors College Thesis
    Full Text:
    :_____________________________________________________ Sean Newsom Type-2 diabetes (T2D) has become a pandemic. The main impairment in T2D is

  • Innovative Bioanalytical Tools & Methods for Combinatorial Non-Coding RNA Analysis

    Creator:
    Zhang, Lulu
    Abstract:
    Recently researchers have discovered that groups of small non-coding RNAs (ncRNAs) play regulatory roles in gene expression and participate in various biological processes. For example, pathogenesis of many diseases, cell cycle regulation, and signaling pathways. Intracellular and live cell imaging of small ncRNA groups will reveal their relative expression levels...
    Resource Type:
    Dissertation
    Full Text:
    Sean M. Burrows Recently researchers have discovered that groups of small non-coding RNAs

  • Displacement-based fluorescent microRNA biosensors : design principles and analytical metrics

    Creator:
    Larkey, Nicholas E.
    Abstract:
    One post-transcriptional mechanism that regulates the progression of cancer and other diseases involves small 22-23 nucleotide sequences called microRNA (miR). Early detection of small changes in concentration of these biomarkers holds potential to diagnose diseases at their earliest stages. Use of current nucleic-acid based biosensors, like molecular beacons, for in...
    Resource Type:
    Dissertation
    Full Text:
    Abstract approved: ______________________________________________________ Sean M. Burrows

  • Gold Nanostars: Spectroscopic and Physical Properties

    Creator:
    Zhou, Lixia
    Abstract:
    Tethering fluorophores on metal nanoparticles for metal enhanced fluorescence (MEF) has attracted a lot of attention from scientists interested in fluorescence based approaches. MEF has many benefits in fluorescence related techniques, because the analytical signal increases and enables potentially lower detection limits or better sensitivity. Many types of nanoparticles have...
    Resource Type:
    Dissertation
    Full Text:
    Sean M. Burrows Tethering fluorophores on metal nanoparticles for metal enhanced

  • CoLocalized Excitation Emission Resolution : A CLEER approach for multicolor fluorescence analysis

    Creator:
    Almlie, C. Kyle
    Abstract:
    Fluorescence has proven to be a robust and powerful method of analysis in numerous fields: forensics, pharmaceutics, geology, food science, and environmental sciences have all developed a large collection of fluorescence instruments and methods to overcome application-specific challenges. Biological applications saw the same development of a fluorescence toolkit with methods...
    Resource Type:
    Dissertation
    Full Text:
    approved: ______________________________________________________ Sean M. Burrows Fluorescence has

  • Improving Bioanalytical Methods of miRNA Analysis and its Applications to Breast Cancer

    Creator:
    Tran, Victoria
    Abstract:
    Micro-ribonucleic acids (miRNA) are becoming an increasingly popular topic of research in hopes of discovering newfound biomarkers and/or therapies for numerous types of cancers and diseases. MiRNA are a type of biomolecule contributing to the progression of multiple cancers and diseases, and such biomolecules are called biomarkers. Current RNA-based biosensors...
    Resource Type:
    Honors College Thesis
    Full Text:
    : ________________________________________________________________________ Sean M. Burrows Micro-ribonucleic acids (miRNA) are becoming an increasingly popular

  • Regulation of muscle fat oxidation and storage by ACSL enzymes and effects of acute exercise training in humans

    Creator:
    Boechler, Victoria
    Abstract:
    The increase in obesity rates in both children and adults in the United States may be a result of impaired or dysregulation of fat metabolism. Long chain acyl-CoA synthetases (ACSLs) may be key regulators of skeletal muscle cell fat metabolism, including fat oxidation and storage. The purpose of the study...
    Resource Type:
    Honors College Thesis
    Full Text:
    humans . Abstract approved:_____________________________________________________ Sean