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Evolution of a Higher Intracellular Oxidizing Environment in Caenorhabditis elegans under Relaxed Selection

Creator:

Joyner-Matos, Joanna, Hicks, Kiley A., Cousins, Dustin, Keller, Michelle, Denver, Dee R., Baer, Charles F., and Estes, Suzanne

Abstract:

We explored the relationship between relaxed selection, oxidative stress, and spontaneous mutation in a set of mutation-accumulation (MA) lines of the nematode Caenorhabditis elegans and in their common ancestor. We measured steady-state levels of free radicals and oxidatively damaged guanosine nucleosides in the somatic tissues of five MA lines for...

Resource Type:

Article

Full Text:

Oxidizing Environment in Caenorhabditis elegans under Relaxed Selection Joanna Joyner-Matos1*., Kiley A