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  • The biologic activity of 5α-reduced pregnanes in the late gestation mare

    Creator:
    Strooband, Jenny A.
    Abstract:
    Mares have an atypical hormone profile during pregnancy. Systemic progesterone (P4) levels approach zero by day 220 of gestation. Other reduced pregnanes such as 5α-pregnane-3, 20-dione (5α), 5α-pregnane-3β, 20α-diol (βα), 3β-hydroxy-5α-pregnan-3-one (3β) and 20α-hydroxy-5α-prenan-3-one (20α), increase to near μg/mL levels in the peripheral system of the mare until directly before...
    Resource Type:
    Masters Thesis
    Full Text:
    an atypical hormone profile during pregnancy. Systemic progesterone (P4) levels approach zero by day

  • Nongenomic action of progesterone inhibits oxytocin signaling through the ovine oxytocin receptor

    Creator:
    Bishop, Cecily V.
    Abstract:
    Experiments were conducted to characterize the nongenomic effects of progesterone (P4) on binding of oxytocin (OT) to the ovine oxytocin receptor (OTR) and signal transduction. The dose-response relationship of P4 to OT binding to the OTR in endometrium was examined. Progesterone interfered with the binding of OT to the OTR...
    Resource Type:
    Dissertation
    Full Text:
    Animal Science presented on June 12, 2006. Title: Nongenomic Action of Progesterone Inhibits Oxytocin

  • Nongenomic inhibition of oxytocin binding by progesterone in ovine uteri

    Creator:
    Dunlap, Kathrin Anson
    Abstract:
    Effects of progesterone (P₄) and mifepristone (RU 486) on binding of oxytocin (OT) to its ovine uterine receptor (OTR) were studied in two experiments. Two additional experiments were conducted to evaluate specific binding sites for P4 in endometrial plasma membranes. In Exp. 1, ovariectomized ewes were injected with estradiol-17β (E₂)...
    Resource Type:
    Masters Thesis
    Full Text:
    Oxytocin Binding by Progesterone in Ovine Uteri. Abstract Approved: Fredrick Stormshak Effects of

  • Effects of conjugated linoleic acids on PGE₂, PGF₂α and progesterone production by bovine luteal cells in vitro

    Creator:
    May, Katherine C. P.
    Abstract:
    Feeding conjugated linoleic acids (CLA) improves reproductive performance in dairy cows; however, the molecular mechanisms by which CLA improves reproduction are not well understood. Therefore, we evaluated whether the CLA isomers, trans-10, cis-12 CLA and cis-9, trans-11 CLA altered synthesis of steroidogenic hormones in bovine luteal cells by measuring concentrations...
    Resource Type:
    Masters Thesis
    Full Text:
    Acids on PGF2α, PGE2 and Progesterone Production