Index Catalog // ScholarsArchive@OSU

The role of costimulation and adjuvants in the development of T cell effector and memory responses

Creator:: Maxwell, Joseph R.
Abstract:: T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
Resource Type:: Dissertation
Full Text:: . The activation of these T cells depends on specific recognition of antigen along with a costimulatory

Factors supporting persistence of academically underprepared community college students

Creator:: Pelkey, Dave
Abstract:: The purpose of this study is to identify factors that support the likelihood of persistence of academically underprepared community college students to 45 college level credits. Factors considered in this research include: (a) race/ethnicity, (b) age, (c) enrollment status, (d) socio-economic status (SES), (e) first quarter GPA, (f) developmental need,...
Resource Type:: Dissertation
Full Text:: considered in this research include: (a) race/ethnicity, (b) age, (c) enrollment status, (d) socio-economic

The influence of aryl hydrocarbon receptor activation on T cell fate

Creator:: Funatake, Castle J.
Abstract:: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds are well-recognized for their immunosuppressive activity, which is mediated through an intracellular receptor and transcription factor, aryl hydrocarbon receptor (AhR). Laboratory animals exposed to TCDD are less resistant to infection and have severely impaired humoral and cell-mediated immune responses. This dissertation addressed the hypothesis that...
Resource Type:: Dissertation
Full Text:: activated antigen-specific T cells. A graft-versus-host (GVH) model, in which T cells from C57B1/6 (B6

Three-Dimensional Network-on-Chip Architectures for Cycle Accurate Full-System Simulator

Creator:: Agarwal, Akash
Abstract:: High Performance Computing can find ubiquitous applications in the industry. HPC-applications are specifically designed to take advantage of the parallel nature of the computing systems which is often enabled by Multi-core/Many-core architectures. With this advent of Multi-processors in the mainstream systems, inter-core communication has been one of the major challenges...
Resource Type:: Presentation and Capstone Project
Full Text:: /documentation/. [Accessed Tuesday May 2020]. 6. T. Krishna, "A Detailed On-Chip Network Model Inside a Full

Turbulent mixing in a strongly forced salt wedge estuary

Creator:: Ralston, David K., Geyer, W. Rockwell, Lerczak, James A., and Scully, Malcolm
Abstract:: Turbulent mixing of salt is examined in a shallow salt wedge estuary with strong fluvial and tidal forcing. A numerical model of the Merrimack River estuary is used to quantify turbulent stress, shear production, and buoyancy flux. Little mixing occurs during flood tides despite strong velocities because bottom boundary layer...
Resource Type:: Article
Full Text:: estuary Turbulent mixing in a strongly forced salt wedge estuary David K. Ralston,1 W. Rockwell Geyer,1

Uncovering the mechanism of IL-4-mediated T cell survival

Creator:: Moscibrocki, Cathleen M.
Abstract:: Although IL-4 is a well-characterized multi-functional cytokine, its role as a survival factor in T cells is not completely understood. In an attempt to uncover IL-4-mediated survival, we studied caspase activation in primary mouse T lymphocytes undergoing death by neglect, activation-induced or steroid-induced cell death. Here, we identify the executioner...
Resource Type:: Masters Thesis
Full Text:: of IL-4-mediated T Cell Survival. Abstract approved: Anthony T. Vella Although IL-4 is a well

Investigations of regulatory T cell induction by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin during a graft-versus-host response

Creator:: Marshall, Nikki B.
Abstract:: The immune toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been studied for over 35 years, but only recently has the profound immune suppression associated with TCDD exposure been linked to induction of regulatory T cells (Tregs). The effects of TCDD are mediated through binding the aryl hydrocarbon receptor (AhR), a ligand-activated transcription...
Resource Type:: Dissertation
Full Text:: induction as a mechanism for suppression of T cell-mediated responses by TCDD

Development of mucosal vaccines for avian influenza A virus composed of recombinant Lactococcus lactis and Streptococcus gordonii

Creator:: Reese, Kaleb A.
Abstract:: Novel mucosal vaccines (LL-M2e, LL-HAe, SG-HAe) were constructed from live, non-pathogenic Lactococcus lactis or Streptococcus gordonii that express conserved regions of HA or M2 antigens from avian influenza virus (AIV) A. All three vaccines evoked antigen-specific serum immunoglobulin G (IgG) responses in vaccinated chickens. The addition of the adjuvant cholera...
Resource Type:: Masters Thesis
Full Text:: AN ABSTRACT OF THE THESIS OF Kaleb A. Reese for the

The Relationship Between IGF-1 and Bone Turnover in a Non-Human Primate Model of Voluntary Alcohol Consumption

Creator:: Sattgast, Lara H.
Abstract:: Alcohol is a widely consumed, nonessential, bioactive nutrient with end-organ effects on the skeleton. Moderate levels of alcohol consumption are generally associated with increased bone mineral density (BMD), whereas higher intake levels result in reduced bone formation, bone loss, and increased risk for osteoporotic fracture. Given the negative impact of...
Resource Type:: Dissertation
Full Text:: . Iwaniec Russell T. Turner Alcohol is a widely consumed, nonessential, bioactive nutrient

"They called me the hyacinth girl" : T. S. Eliot, masculinity, and the Great War

Creator:: Query, Patrick
Abstract:: This thesis traces the relationship between the First World War, constructions of masculinity, and the life and poetry of T.S. Eliot. Central to this relationship is a study of homoeroticism, which the author characterizes as different from homosexuality but not exclusive of it, in late 19th and early 20th century...
Resource Type:: Masters Thesis
Full Text:: "They called me the hyacinth girl" : T. S. Eliot, masculinity

ScholarsArchive@OSU

The role of costimulation and adjuvants in the development of T cell effector and memory responses

Factors supporting persistence of academically underprepared community college students

The influence of aryl hydrocarbon receptor activation on T cell fate

Three-Dimensional Network-on-Chip Architectures for Cycle Accurate Full-System Simulator

Turbulent mixing in a strongly forced salt wedge estuary

Uncovering the mechanism of IL-4-mediated T cell survival

Investigations of regulatory T cell induction by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin during a graft-versus-host response

Development of mucosal vaccines for avian influenza A virus composed of recombinant Lactococcus lactis and Streptococcus gordonii

The Relationship Between IGF-1 and Bone Turnover in a Non-Human Primate Model of Voluntary Alcohol Consumption

"They called me the hyacinth girl" : T. S. Eliot, masculinity, and the Great War

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