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Creator:: Watson, G. W., Wickramasekara, S., Palomera-Sanchez, Z., Black, C., Maier, C. S., Williams, D. E., Dashwood, R. H., and Ho, E.
Abstract:: The isothiocyanate sulforaphane is a promising molecule for development as a therapeutic agent for patients with metastatic prostate cancer. Sulforaphane induces apoptosis in advanced prostate cancer cells, slows disease progression in vivo and is well tolerated at pharmacological doses. However, the underlying mechanism(s) responsible for cancer suppression remain to be...
Full Text:: -induced apoptotic signaling in PC3 prostate cancer cells Watson, G. W., Wickramasekara, S., Palomera

Creator:: Watson, G. W., Wickramasekara, S., Palomera-Sanchez, Z., Black, C., Maier, C. S., Williams, D. E., Dashwood, R. H., and Ho, E.
Abstract:: The isothiocyanate sulforaphane is a promising molecule for development as a therapeutic agent for patients with metastatic prostate cancer. Sulforaphane induces apoptosis in advanced prostate cancer cells, slows disease progression in vivo and is well tolerated at pharmacological doses. However, the underlying mechanism(s) responsible for cancer suppression remain to be...
Resource Type:: Article

Creator:: Watson, G. W., Wickramasekara, S., Palomera-Sanchez, Z., Black, C., Maier, C. S., Williams, D. E., Dashwood, R. H., and Ho, E.
Abstract:: The isothiocyanate sulforaphane is a promising molecule for development as a therapeutic agent for patients with metastatic prostate cancer. Sulforaphane induces apoptosis in advanced prostate cancer cells, slows disease progression in vivo and is well tolerated at pharmacological doses. However, the underlying mechanism(s) responsible for cancer suppression remain to be...

Creator:: Milovancev, Milan, Hilgart-Martiszus, Ian, McNamara, Michael J., Goodall, Cheri P., Seguin, Bernard, Bracha, Shay, and Wickramasekara, Samanthi I.
Abstract:: Background: Osteosarcoma (OSA) is the most common primary bone tumor of dogs and carries a poor prognosis despite aggressive treatment. An improved understanding of the biology of OSA is critically needed to allow for development of novel diagnostic, prognostic, and therapeutic tools. The surface-exposed proteome (SEP) of a cancerous cell...
Resource Type:: Article
Full Text:: author(s) declare that they have no competing interests. Authors’ contributions All authors (MM, IHM

Creator:: Tzeng, Shin-Cheng and Maier, Claudia S.
Abstract:: The analysis of oxidative stress-induced post-translational modifications remains challenging due to the chemical diversity of these modifications, the possibility of the presence of positional isomers and the low stoichiometry of the modified proteins present in a cell or tissue proteome. Alcoholic liver disease (ALD) is a multifactorial disease in which...
Resource Type:: Article
Full Text:: , USA *Correspondence: Claudia S. Maier claudia.maier@oregonstate.edu † Present Address: Shin-Cheng

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