Tyrosine kinases mediate response of blood cells to stimuli and small molecule tyrosine kinase inhibitors (TKIs) serve important roles as drugs in managing hematological diseases. In healthy B cells, the B cell receptor (BCR) activates a tyrosine kinase known as Syk, which then activates BTK, PI3K, PLC2 and protein kinase...
Predicting recruitment, which is dependent on parent stock size and climate, is vital for forecasting productivity of fish stocks. The effects of climate can be analyzed via the use of climate indices. Three climate indices, the Pacific Decadal Oscillation, the North Pacific Gyre Oscillation, and the Oceanic Niño Index, describe...
This study presents a mooring analysis of the Ocean Sentinel buoy, which is a mobile test platform for Wave Energy Converters. The Ocean Sentinel is owned and operated by the Northwest National Marine Renewable Energy Center (NNMREC) at Oregon State University (OSU). The study involved a field observation as well...
The advance of digital IC technology has been very fast, as shown by rapid development of DSP, digital communication and digital VLSI. Within electronic signal processing, analog-to-digital conversion is a key function, which converts the analog signal into digital form for further processing. Recently, low-voltage and low-power have become also...
Surface sediment transport is an important geomorphic process which can be significantly altered by management activities in forested ecosystems. Disturbance of the soil surface may result in increased sediment delivery to fish bearing streams and degradation of soil structure. Selective thinning and low impact yarding techniques were utilized in an...
Motion planning is a cornerstone of autonomous robots, enabling robots to safely and efficiently perform tasks such as package delivery, infrastructure inspection, and manipulation. However, as the field of robotics matures, robotic systems are being developed that (1) are challenging to analytically model, (2) require computationally expensive model-based controllers, and...
Extreme weather events are expected to increase globally due to climate change thereby posing substantial risks to agricultural communities. The implications are especially high for tropical countries like India as the heavy dependence of agricultural sector to uncertain monsoons makes its agriculture highly vulnerable to weather variability and extremes. In...
The seismic response of deep deposits of liquefiable and cyclic-softening susceptible soils has presented the geotechnical profession with significant engineering challenges. Strong ground motions may serve to soften soils under cyclic shear, trigger liquefaction, and produce damaging displacements as a consequence. This study improves the understanding of the in-situ, nonlinear,...
The human intervertebral disc is a deceptively simple structure which plays an essential role in human movement. Even slight changes to the disc microenvironment can have far reaching consequences, particularly when these changes result in disc degeneration and herniation. Degeneration is increasingly tied to lower back pain; better understanding this...
This dissertation consists of a general introduction, three research manuscripts, and general conclusions regarding the mapping of quantitative trait loci (QTLs) for sustainability traits in the Triticeae Coordinated Agricultural Project (TCAP) facultative/winter 6-rowed elite malting barley genome-wide association studies (GWAS) mapping panel, the TCAP FAC-WIN6. The first research manuscript, a...