Small molecule drugs have been instrumental in our fight against diseases, beginning when some of the earliest ancient cultures used plant remedies to treat illnesses. More recently, the skill of isolating and characterizing the active ingredients within bioactive plants and microbial extracts has led to the isolation and design of...
Intracellular delivery of mRNA holds great potential for vaccine and therapeutic discovery and development. This is realized by the preeminent role mRNA is playing in the record-breaking pace of SARS-CoV-19 vaccine development. Recent advances in chemical modifications of mRNA have enabled high-efficiency gene expression with superior spatiotemporal control while eliminating...
While human tool-use proficiency helped define our history, the cognitive and perceptual mechanics of how humans use tools are not fully understood. This question is of great value to the design of hand-held tools and prosthetics. A prominent theory, tool embodiment, suggests that tool use is facilitated by a flexible...
My dissertation title is, “Applied economic strategies to evaluate policies and environmental outcomes: case studies from immigration and ecosystem services.” The first two chapters of this dissertation concern the relationship between local immigration policies and societal welfare. The third chapter examines the impact of human activity on the environment and...
The Roger Revelle Commemorative Lecture Series was created by the Ocean Studies Board of the National Academies in honor of Roger Revelle to highlight the important links between ocean sciences and public policy. Dawn J. Wright, the eighteenth annual lecturer, spoke on April 28, 2017, at the Smithsonian National Museum...
Mass timber is emerging as a viable form of construction around the world in new markets for wood buildings. The entrance into these markets has driven the demand for more knowledge to enable designs alongside other structural materials such as steel and reinforced concrete.
Large, in-plane tests on cross-laminated timber...
The existence, sources, distribution, circulation, and physicochemical nature of macroscale oceanic water bodies have long been a focus of oceanographic inquiry. Building on that work, this paper describes an objectively derived and globally comprehensive set of 37 distinct volumetric region units, called ecological marine units (EMUs). They are constructed on...
Innovation is critical for firm growth and survival. Thus, how much value firms create and capture from their innovative activities has been an interest of scholars. This dissertation explores three important questions on this topic to which extant literature has paid little attention. First, I examine how the external threat...
Natural durability remains one of the most attractive characteristics of wood, and helps wood obtain a premium price. A worldwide shift towards the use of younger trees from intensively managed forests has created greater concerns about wood quality, especially the wood’s resistance to fungi and insects. Wood durability is assessed...
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Jeffrey J. Morrell
Natural durability remains one of the most attractive characteristics of
Ecological restoration is needed to mitigate losses to biodiversity. Restoration success is enhanced through the use of native plant materials that are genetically diverse and locally adapted. Seed transfer zones have been developed to delineate geographic areas where native seed can be collected and distributed with reduced risk of maladaptation....