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  • Monotonic and Cyclic Testing of Cross-Laminated Timber Diaphragms

    Creator:
    Beairsto, Cody J.
    Abstract:
    Mass timber is emerging as a viable form of construction around the world in new markets for wood buildings. The entrance into these markets has driven the demand for more knowledge to enable designs alongside other structural materials such as steel and reinforced concrete. Large, in-plane tests on cross-laminated timber...
    Resource Type:
    Masters Thesis
    Full Text:
    : ______________________________________________________ Rakesh Gupta Thomas H. Miller Abstract Mass timber is emerging as a viable form of

  • New Treatments for HIV and Cancer: Uncovering Bioactive Compounds from Small Molecule Sources

    Creator:
    Overacker, Ross D.
    Abstract:
    Small molecule drugs have been instrumental in our fight against diseases, beginning when some of the earliest ancient cultures used plant remedies to treat illnesses. More recently, the skill of isolating and characterizing the active ingredients within bioactive plants and microbial extracts has led to the isolation and design of...
    Resource Type:
    Dissertation
    Full Text:
    level inhibition (∼7 µM) of HIV-1 by acting on the RNase H activity of the viral reverse transcriptase

  • Boosting Intracellular Delivery of mRNA Therapeutics

    Creator:
    Patel, Siddharth D.
    Abstract:
    Intracellular delivery of mRNA holds great potential for vaccine and therapeutic discovery and development. This is realized by the preeminent role mRNA is playing in the record-breaking pace of SARS-CoV-19 vaccine development. Recent advances in chemical modifications of mRNA have enabled high-efficiency gene expression with superior spatiotemporal control while eliminating...
    Resource Type:
    Dissertation
    Full Text:
    the retina showed a rapid onset (within 4 hr) that persisted for 96 h. The gene delivery was cell

  • Porous metal-organic materials for gas capture

    Creator:
    Rookard, Tanner Daniel
    Abstract:
    Metal-organic polyhedra (MOPs) are discrete molecules comprised of a metal and interconnecting ligands. The resulting MOP structures are porous cages, and to date, they have shown great promise toward gas capture. Ammonia is a hazardous gas that is produced in enormous quantities for use in fertilizers. In this talk, I...
    Resource Type:
    Capstone Project
    Full Text:
    ligands used for this study are pristine isophthalic acid (H-Rh MOP), hydroxyl-functionalized

  • Evaluation of Low-Impact Development (LID) Treatment Train at OSU-Benton County Green Infrastructure Facility

    Creator:
    Saduova, Alisha
    Abstract:
    Urban stormwater runoff with a high impervious area can significantly impact pollution concentrations of receiving water bodies. The use of low impact development (LID), which mimics the hydrological properties of the site before development, has been studied in an increasing number of studies, and the available database has shown to...
    Resource Type:
    Masters Thesis

  • A socio-technical study on the improved characterization of stakeholder behaviors and stream temperature in design of watershed conservation practices for climate change adaptation

    Creator:
    Noa-Yarasca, Efrain
    Abstract:
    Characterizing stakeholder behavior when making decisions in watershed management is a great challenge for planners, not only because plans are associated with physical uncertainties but also because stakeholders’ behaviors are influenced by numerous factors. Since stakeholders’ decision-making is linked to multiple types of uncertainty, communication of uncertainty to stakeholders by...
    Resource Type:
    Dissertation
    Full Text:
    ; Heilman & Kusev, 2020; S. Schwartz, 2012; S. H. Schwartz, 2006). Multiple theories have been proposed to

  • Transdermal Delivery of Atenolol to Cats

    Creator:
    Mohamed, Sumeia M.
    Abstract:
    This thesis describes in-vitro and in-vivo evaluation of a transdermal atenolol formulation developed at Oregon State University, College of Pharmacy. The formulation was prepared from carbomer as a gel base with propylene glycol, glycerol, ethanol, polysorbate 80 and dimethyl-isosorbide (DMI) as mixture of penetration enhancing agents. The effect of the...
    Resource Type:
    Dissertation
    Full Text:
    demonstrated two fluxes, the burst flux (15.7μg/cm2/h) and a sustained flux (2.7μg/cm2/h