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Filtering by: Creator Robinson, Robert Remove constraint Creator: Robinson, Robert Rights Statement In Copyright - Educational Use Permitted Remove constraint Rights Statement: In Copyright - Educational Use Permitted

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  • Boosting Intracellular Delivery of mRNA Therapeutics

    Creator:
    Patel, Siddharth D.
    Abstract:
    Intracellular delivery of mRNA holds great potential for vaccine and therapeutic discovery and development. This is realized by the preeminent role mRNA is playing in the record-breaking pace of SARS-CoV-19 vaccine development. Recent advances in chemical modifications of mRNA have enabled high-efficiency gene expression with superior spatiotemporal control while eliminating...
    Resource Type:
    Dissertation
    Full Text:
    . Oleh Taratula, Dr. Susan Tilton, and Dr. Robert Allen for their time and interdisciplinary advice. I

  • Efficacy of Empirical Seed Zones: Pseudoroegneria Spicata Reproductive Phenology & Seedling Stage Traits

    Creator:
    Prive, Kathryn A.
    Abstract:
    Ecological restoration is needed to mitigate losses to biodiversity. Restoration success is enhanced through the use of native plant materials that are genetically diverse and locally adapted. Seed transfer zones have been developed to delineate geographic areas where native seed can be collected and distributed with reduced risk of maladaptation....
    Resource Type:
    Masters Thesis
    Full Text:
    . M., Bakker, J. D., Dettweiler-Robinson, E., Dunwiddie, P. W., Hall, S. A., Downs, J., & Evans, J

  • New Treatments for HIV and Cancer: Uncovering Bioactive Compounds from Small Molecule Sources

    Creator:
    Overacker, Ross D.
    Abstract:
    Small molecule drugs have been instrumental in our fight against diseases, beginning when some of the earliest ancient cultures used plant remedies to treat illnesses. More recently, the skill of isolating and characterizing the active ingredients within bioactive plants and microbial extracts has led to the isolation and design of...
    Resource Type:
    Dissertation