Gene regulation is a complex mechanism that controls the spatial and temporal expression of genes in a living cell. My dissertation studies focus on two problems. First, tissue-specific gene expression prediction from DNA sequence and chromatin state, and second, the accurate discovery of small over-represented regulatory circuits in gene regulatory...
Specialized or secondary metabolism is a collection of pathways and small molecules that, while beneficial to an organism, are not strictly necessary for survival. Plants use secondary metabolites to, among other things, attract pollinators, defend against biotic and abiotic stressors, and form symbioses. Natural products from plants have seen an...
Drought events have been shown to impact species distributions and are predicted to increase in frequency as the climate changes. As this occurs, ecologists predict species distributions will shift dependent upon species ability to track climate. These shifts in species distribution are expected to be particularly acute in arid and...
Managers of U. S. Fish and Wildlife Service’s Bald Knob National Wildlife Refuge (Refuge) in central Arkansas want to provide sufficient habitat resources to meet its population objectives for wintering waterfowl. Nutrient reserves acquired during the wintering period appear to support spring migration and subsequent reproductive success for some species,...
Contextualization is a curricular approach and a learning process in which science content knowledge is intentionally situated within a context where that knowledge can be authentically applied or observed. Many recent science education reforms include contextualization as a central tenet. Our goal in this review was to examine commonalities across...
In Oregon perennial and annual grass seed cropping systems conservation management practices and their impacts on soil health and soil microbial community is not well understood. There is strong motivation to employ conservation tillage and other conservation practices to curb atmospheric carbon levels and improve soil health. However, the few...
Summertime low clouds are common in the Pacific Northwest (PNW), but spatiotemporal patterns have not been characterized. We show the first maps of low cloudiness for the western PNW and North Pacific Ocean using a 22‐year satellite‐derived record of monthly mean low cloudiness frequency for May through September and supplemented...
Null networks are a type of random graph that is favored for the analysis of a wide variety of real-world networks, including gene-regulatory networks, food webs, and species co-occurrence matrices. As a hypothesis-generating tool, null networks are invaluable because they can reveal network motifs and unusual large-scale properties of networks...
Ph.D. candidate Qi Wei's thesis consists of two projects: Chemotherapy Project: a study based on the research paper "Predicting chemotherapy response of various cancer types using a variational auto-encoder approach" submitted to the bioRxiv preprint archive and accepted by the BMC bioinformatics; and Wound Monitor Project: implementing and assessing analytics...