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Computational Approaches for Understanding Combinatorial Gene Regulation

Creator:

Ansariola, Mitra

Abstract:

Gene regulation is a complex mechanism that controls the spatial and temporal expression of genes in a living cell. My dissertation studies focus on two problems. First, tissue-specific gene expression prediction from DNA sequence and chromatin state, and second, the accurate discovery of small over-represented regulatory circuits in gene regulatory...

Resource Type:

Dissertation
Measurement of the muon antineutrino double-differential cross section for quasielastic-like scattering on hydrocarbon at Eν ∼ 3.5 GeV

Creator:

Schellman, Heidi, Fields, Laura J., and Patrick, Cheryl E.

Abstract:

We present double-differential measurements of antineutrino charged-current quasielastic scattering in the MINERvA detector. This study improves on a previous single-differential measurement by using updated reconstruction algorithms and interaction models and provides a complete description of observed muon kinematics in the form of a double-differential cross section with respect to muon...

Resource Type:

Article

Full Text:

. Gallagher,13 A. Ghosh,12,8 R. Gran,14 J. Y. Han,10 D. A. Harris,5 S. Henry,6 K. Hurtado,8,9 D. Jena,5 J
Investigating Transcriptional Control of Specialized Gene Expression in Plants

Creator:

Fraser, Valerie N.

Abstract:

Specialized or secondary metabolism is a collection of pathways and small molecules that, while beneficial to an organism, are not strictly necessary for survival. Plants use secondary metabolites to, among other things, attract pollinators, defend against biotic and abiotic stressors, and form symbioses. Natural products from plants have seen an...

Resource Type:

Dissertation