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Computational Approaches for Understanding Combinatorial Gene Regulation

Creator:

Ansariola, Mitra

Abstract:

Gene regulation is a complex mechanism that controls the spatial and temporal expression of genes in a living cell. My dissertation studies focus on two problems. First, tissue-specific gene expression prediction from DNA sequence and chromatin state, and second, the accurate discovery of small over-represented regulatory circuits in gene regulatory...

Resource Type:

Dissertation
Machine Learning for Precision Medicine: Application to Cancer Chemotherapy Response Prediction and Wound Healing Status Assessment

Creator:

Wei, Qi

Abstract:

Ph.D. candidate Qi Wei's thesis consists of two projects: Chemotherapy Project: a study based on the research paper "Predicting chemotherapy response of various cancer types using a variational auto-encoder approach" submitted to the bioRxiv preprint archive and accepted by the BMC bioinformatics; and Wound Monitor Project: implementing and assessing analytics...

Resource Type:

Dissertation

Full Text:

3.5.3 Time-series measurements of C-reactive protein (CRP), Im- munoglobulin G (IgG) can be integrated