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Filtering by: Advisor Gable, Kevin Subject Alkaloids -- Synthesis

Studies toward the total synthesis of alkaloids : nagelamide A and D, agelastatin D, dragmacidin A-C, salacin and almazoles

Creator:

Tonsiengsom, Sorasaree

Abstract:

Studies toward the total syntheses of highly potent cytotoxic alkaloids including the bromopyrrole alkaloids and indole alkaloids were conducted and are described. Studies carried out in the course of this dissertation consist of five total syntheses of natural products that include bromopyrrole alkaloids nagelamide A, D and agelastatin D as...

Resource Type:

Dissertation

Full Text:

, SALACIN AND ALMAZOLES Abstract approved: Kevin P. Gable Studies
Studies on nitrogen containing secondary metabolites from terrestrial and marine origin

Creator:

Barrios Sosa, Ana Carolina

Abstract:

PART I. A deuterium exchange analysis of 2,5-dihydroxyacetanilide (5) in the absence and presence of DHAE II was performed to test the nucleophilicity of the substrate in the absence and presence of catalyst. In addition, inhibition studies using 1,4-dihydroxybenzene were performed to determine the role that the N-acetyl side chain...

Resource Type:

Dissertation

Full Text:

Abstract approved: David A. Home Kevin P. Gable PART I. A deutenum exchange analysis of 2,5