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Filtering by: Subject Amino acids -- Synthesis

The biosynthesis of aromatic amino acids in yeast (Saccharomyces cerevisiae)

Creator:

Thomas, Richard Clarence

Resource Type:

Dissertation
Studies on advanced intermediates in the biosynthesis of streptonigrin

Creator:

Erickson, W. Randal

Abstract:

Early studies on the biosynthesis of the quinoline quinone portion of streptonigrin, 1, had suggested the intermediacy of novel aromatic amino acids. In order to test this hypothesis, a series of compounds was synthesized and tested for potential incorporation. [4-¹⁵N] 4-Aminoanthranilic acid, 4 5 a , [4-² H] 7-aminoquinaldinic acid,...

Resource Type:

Dissertation
Formation and modification of enduracididine, a nonproteinogenic amino acid

Creator:

Tan, Ying

Abstract:

Molecular genetic and enzymological techniques have been employed to study antibiotic biosynthesis. In this thesis, we studied the formation and modification of the nonproteinogenic amino acid enduracididine (End), which exists in two important antibiotics, mannopeptimycins (MPPs) and enduracidin. Sequence analysis of the MPP gene cluster revealed that the product of...

Resource Type:

Masters Thesis