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Filtering by: Subject Streptomyces Subject Antineoplastic agents -- Synthesis

Biosynthesis of acivicin and 4-hydroxyacivicin

Creator:

Ju, Shyh-chen

Resource Type:

Dissertation
Biosynthetic engineering of new pactamycins

Creator:

Lu, Wanli

Abstract:

Among the myriad of naturally occurring bioactive compounds are the aminocyclopentitol-containing natural products that represent a family of sugar-derived microbial secondary metabolites, such as the antibiotics pactamycin, allosamidin, and trehazolin. Pactamycin, a structurally unique aminocyclitol antibiotic isolated from Streptomyces pactum, consists of a 5-membered ring aminocyclitol (cyclopentitol) unit, two aromatic...

Resource Type:

Dissertation