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Filtering by: Committee Member Valentine, Milton A. Remove constraint Committee Member: Valentine, Milton A. Subject Antitubercular agents Remove constraint Subject: Antitubercular agents

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  • Acute exposure to ethionamide in an Fmo 1/2/4 null murine model

    Creator:
    Palmer, Amy L.
    Abstract:
    The use of ethionamide has been increasing in drug regiments due to greater incidence of multidrug resistance tuberculosis around the world. Ethionamide is metabolized into antimicrobial relevant compounds by different flavin-containing monooxygenase (FMO) enzymes including FMO1, FMO2, and FMO3. FMOs are found in various locations in the body including the...
    Resource Type:
    Masters Thesis