Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Subject Atherosclerosis -- Etiology

The role of copper and its chelation by tetrathiomolybdate in inflammation and atherosclerosis

Creator:

Wei, Hao

Abstract:

Endothelial activation with increased expression of cellular adhesion molecules, chemokines and pro-inflammatory cytokines critically contributes to vascular inflammation and the initiation and progression of atherosclerosis. By affecting redox-sensitive cell signaling pathways and transcription factors, redox-active transition metal ions, such as copper and iron, may play an important role in these...

Resource Type:

Dissertation