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Filtering by: Creator Huss, Christiana H. Subject Bacteriophage T4

Organization of the T4 dNTP synthetase complex at DNA replication sites

Creator:

Kim, JuHyun

Abstract:

With respect to a multienzyme complex of deoxyribonucleoside triphosphate (dNTP) synthesis somehow juxtaposed with DNA replication sites, our laboratory has demonstrated the existence of a multienzyme complex in T4-infected E. coli, named the T4 dNTP synthetase complex, but the idea of direct linkage of dNTP synthesis to DNA replication and...

Resource Type:

Dissertation

Full Text:

32 43 44 45 61 62 46 uvsX uvsY pseT f3gt/ RI'/ase H dCMP HMase dTMP synthase DHF
Host kinases involved in DNA precursor biosynthesis during bacteriophage T4 infection

Creator:

Bernard, Mark Aguirre

Abstract:

Although the Escherichia coli host has almost all of the enzymes necessary to synthesize nucleotides needed for bacteriophage T4 DNA replication, phage genes expressed early in infection encode enzymes for de novo DNA precursor biosynthesis and salvage from degraded host DNA. Eight early enzymes and two host enzymes comprise the...

Resource Type:

Dissertation