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Filtering by: Creator L’Heureux, K. Remove constraint Creator: L’Heureux, K. Subject Bacteriophage T4 Remove constraint Subject: Bacteriophage T4

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  • Deoxyribonucleotides as determinants of DNA replication fidelity in bacteriophage T4

    Creator:
    Sargent, Roy Geoffrey
    Abstract:
    Imbalanced deoxyribonucleoside triphosphate (dNTP) pools are mutagenic for DNA synthesis in both intact cells and cell-free replication systems. Almost certainly, such mutagenesis involves competition between correctly and incorrectly base-paired precursors at replication sites. However, there are certain differences between the intact cell and cell-free systems that do not always allow...
    Resource Type:
    Dissertation
    Full Text:
    privacy Christopher K. Mathews Imbalanced deoxyribonucleoside triphosphate (dNTP) pools are mutagenic