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Filtering by: Creator Yeh, Li-Hsien Subject Calpain

Effects of age, castration and gestation on calpains and calpastatin in sheep and rabbit skeletal muscle

Creator:

Ou, Bor-rung

Abstract:

Objectives of this study were to examine effects of age, castration and gestation on actvities of calpains and calpastatin in skeletal muscle. Also, the regulation of calpains and calpastatin at the molecular level was investigated. Two experiments were designed. Experiment 1 was designed to evaluate effects of age and castration...

Resource Type:

Masters Thesis

Full Text:

Yeh for Bor-rung Ou Acknowledgement I would like to begin by thanking Dr. Forsberg for his
The role of calpains in muscle protein degradation

Creator:

Ou, Bor-rung

Resource Type:

Dissertation
Coordination of protease systems on muscle protein degradation and identification of calpain substrates using the yeast two-hybrid system

Creator:

Purintrapiban, Juntipa

Abstract:

The first goal of this study was to evaluate the roles of different intracellular proteolytic systems in accelerated skeletal muscle protein degradation. Total, myofibrillar and non-myofibrillar proteolysis were determined in cultured L8/CID muscle cells. Calpain proteolysis was assessed by over-expressed calpastatin inhibitory domain (CD). Lysosomal proteolysis was determined in the...

Resource Type:

Dissertation

Full Text:

and its inhibitor, p18 (Guan et al., 1994), c-jun/c-fos (Kato et al., 1992), p53/T-antigen (Li and