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Filtering by: Subject Cancer -- Chemotherapy

A comparison of the effect of pH change upon the uptake of 5-fluorouracil into rat liver and Walker 256 carcinosarcoma slices

Creator:

Hult, Richard Lee

Abstract:

An enhancement of the therapeutic effect and/or a reduction in the toxicity have been shown by a variety of antineoplastic compounds when glucose is added to the treatment schedule. A possible explanation for this involves a selective change in intracellular pH of the tumor tissue initiating a greater uptake of...

Resource Type:

Masters Thesis
1) Improving the Uptake and Retention of Gadolinium in Tumors for Potential Gadolinium-Neutron Capture Therapy. 2) Integration of Gemcitabine or Localized Irradiation into dsRNA Therapy Significantly Enhanced the Resultant Anti-tumor Activity

Creator:

Le, Uyen Minh

Abstract:

Cancer is one of the leading causes of death in the U.S., and new approaches to control cancer are constantly sought. This dissertation is comprised of two parts: (i) improving the uptake and retention of gadolinium in tumors for potential gadoliniumneutron capture therapy (Gd-NCT) and (ii) integration of gemcitabine or...

Resource Type:

Dissertation