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Filtering by: Creator Hedstrom, Christopher Subject Cancer -- Immunological aspects Subject Indole -- Physiological effect

Chronic exposure of rodents to indole-3-carbinol and 3,3'-diindolylmethane : implications for drug metabolism, chemoprevention and human health

Creator:

Leibelt, Dustin A.

Abstract:

Indole-3-carbinol (I3C) is a naturally occurring plant alkaloid, found in significant concentrations in cruciferous vegetables such as broccoli and Brussels sprouts. I3C is an unstable compound that undergoes rapid oligomerization in an acidic environment to form higher order condensation products (I3C-ACPs), such as 3-3'-diindolylmethane (DIM). Both I3C and DIM are...

Resource Type:

Dissertation

Full Text:

support. I thank Drs. Donald Reed, Balz Frei, Philip Whanger, and Christopher Bayne for serving as