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Filtering by: Creator Tuan, Le Anh Remove constraint Creator: Tuan, Le Anh Subject Chromatin Remove constraint Subject: Chromatin

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  • Physico-chemical studies on the structure of eukaryotic chromatin

    Creator:
    Sahasrabuddhe, Chintaman Gopal
    Abstract:
    It has been shown that about 50 % of the whole chromatin DNA exists in a very compact form in calfthymus chromatin.These compact fragments can be extracted from the whole chromatin as nuclease resistant fragments by limited nuclease digestion. These fragments involve four out of five histones in folding the...
    Resource Type:
    Dissertation
    Full Text:
    Panyim,Jensen and Chalkley(1968).Elgin and Bonner found that about 10-15 proteins make up at le- ast

  • Physical studies of the yeast inner histones

    Creator:
    Mardian, James Kenneth Walker
    Abstract:
    In this work, the four yeast inner histones were prepared by the use of consecutive slab gel fractionation. The use of this technique allowed the first complete fractionation and rigorous identification of the four yeast inner histones, and made possible a study of their complexing behavior. Variants and adjuncts of...
    Resource Type:
    Dissertation
    Full Text:
    Hnilica, 1965; Tuan and Bonner, 1969; Boublik et al., 1970a, b; Li et al., 1972; Wickett et al. , 1972

  • Physical structure and reconstitution of chromatin core particles

    Creator:
    Tatchell, Kelly George
    Abstract:
    The nucleosome appears to be the basic structural unit of the eukaryotic chromosome. The usual nucleosome preparation, isolated from a micrococcal nuclease digest of nuclei, is heterogenous in DNA length and protein composition with some particles containing spacer DNA and associated protein. This heterogeneity complicated physical and reconstitution studies. As...
    Resource Type:
    Dissertation

  • The binding of ethidium bromide to chromatin : model for carcinogen interactions

    Creator:
    McMurray, Cynthia T.
    Abstract:
    Five forms of chromatin, which represent the in vivo folded forms of nucleic acid, were isolated and used as the binding substrate for model intercalating compound, ethidium bromide. For all forms of chromatin, the affinity, location and structural effects of binding were examined. On the level of the nucleosome, the...
    Resource Type:
    Dissertation
    Full Text:
    , planar molecules insert between the base pairs of DNA (Fuller and Waring, 1964; Waring, 1970; Le Pecq