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Creator:: Zangar, Richard Carl, 1958-
Resource Type:: Dissertation
Full Text:: Xenobiotics in the Rat Abstract approved: Redacted for Privacy uonala R. Burlier Adult hepatic metabolism

Creator:: Lee, Su-Jun
Resource Type:: Dissertation
Full Text:: Privacy Redacted for Privacy ACKNOWLEDGMENTS I would like to give my thanks to Dr. Donald R. Buhler

Creator:: Chen, Shiu-ling
Resource Type:: Masters Thesis
Full Text:: Abstract approved: Redacted for Privacy Donald R. Buhler Both trout and mammals are susceptible to

Creator:: Schlenk, Daniel K.
Abstract:: Aquatic animals are exposed to a variety of natural and anthropogenic xenobiotics. Biotransformation of xenobiotics was examined in three aquatic animals: a primitive mollusc (chiton); a shellfish which is an important human food source (oyster); and, a lower vertebrate model for toxicological studies (rainbow trout). Since digestive glands of Cryntochiton...
Resource Type:: Dissertation
Full Text:: Abstract approved: Donald R. Buhler Aquatic animals are exposed to a variety of natural and

Creator:: Hawkins, Jenna M.
Abstract:: Non-alcoholic Steatohepatitis (NASH) is an emerging form of liver disease associated with obesity, type II diabetes and dyslipidemia. As the prevalence of these metabolic conditions increases, so too has the occurrence of NASH in all sectors of the population. The pathology of this disease is similar to its alcoholic form,...
Resource Type:: Honors College Thesis
Full Text:: scheme: NADPH + H+ + R + O2  NADP+ + H2O + ROH (R= substrate, ROH= product) In mammals the

Creator:: Harris, Marcia Elaine
Abstract:: The induction of drug-metabolizing enzymes is a complex biochemical process manifested not only by increases in various cytochrome P-450 isozymes and related activities, but also by alterations in endoplasmic reticulum membranes. Little work has been done to examine how cytochrome P-450 inducing agents influence other cellular processes, such as phospholipid...
Resource Type:: Masters Thesis
Full Text:: * I P-450 RH-Fe3+ (ROH)Fe3+ R-(Fe-OH) 6 RH(Fe-0)3+ H20A 2H+ \ RH-Fe3+(02) RH-Fe2

Creator:: Baldridge, Gerald D.
Abstract:: A sucrose density-gradient ultracentrifugation technique for obtaining microsomes has been developed. This technique has advantages over the classic differential centrifugation technique, in that it is faster, is better suited to work with small quantities of tissue, and offers the opportunity to work with a defined microsomal sub-cellular fraction, rather than...
Resource Type:: Masters Thesis
Full Text:: she, also, was busy preparing a thesis. This work was supported by NIH grant AI 19192 to Dr. R

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